Antibiotic all in one

Question 1

imipenem-cilaststin

Answer 1

Broad spectrum antibiotic
Monitor seizures, CNS problem
Cannot be given IM because of the lidocaine involve

Question 2

aztreonam

Answer 2

BUN 7 to 20 mg/dL

Question 3

gentamicin

Answer 3

BBW: nephrotoxicity and ototoxicity
trough – I would check that when I’m getting ready to give the next dose
always right before you give a dose
peak – check peak two hrs after you give a dose do not infuse with any other drug
IV 30 minutes to 1hr

Question 4

ciprofloxacin

Answer 4

a. BBW: tendon rupture
b. Take 2hrs before, 6hrs after antacid
c. Prolong the QT interval and may increase the risks of torsade de pointes and sudden death

Question 5

tetracycline hydrochloride

Answer 5

a. Digoxin toxicity, photosensitivity
b. Can cross placenta, cross breast milk, grey baby teeth: teratogenic effect
c. If you mix it with another drug, you can get digoxin toxicity

Question 6

Erythromycin

Answer 6

i. Cardiac effects, with the IV form-possible ventricular dysrhythmias.
i. No grapefruit juice and St John’s wort. Give 1 hr before or 2 hr after meals. Full glass of water. Take at equal intervals.

Question 7

metronidazole

Answer 7

a. no alcohol: big education piece
b. metallic taste.
c. Very rough on the body

Question 8

Isoniazid (INH)

Answer 8

a. TB med
b. Tingling, weakness, and numbness
c. BBW: hepatitis
d. Education: Monitor LFT, No phenytoin. Give before meals.

Question 9

rifampin (RIF),

Answer 9

a. TB med
b. orange fluid
c. use additional contraception
d. difficult on the liver, discoloration of urine

Question 10

acyclovir

Answer 10

a. Use: Drugs for herpes simplex and varicella-zoster virus- antivirals
i. Herpes simplex virus and varicella zoster
b. Check renal and liver labs: hardest on renal, (I/O monitor), may cause edema
c. You cannot crush it!

Question 11

zidovudine (AZT)

Answer 11

a. HIV
b. Report any side effect,
c. They should take the drug around the clock to avoid variations in serum peak and trough levels.

Question 12

amphotericin B deoxycholate

Answer 12

a. Use: To treat progressive and potentially fatal fungal infections.
b. monitor for fever, chills, injection or IV (infusion) site, vitals, temperature
c. LAST RESORT DRUG. very toxic, if we have a choice, we will choose something else

Question 13

fluconazole

Answer 13

a. Adverse effect: Elevation of liver enzymes and hepatoctoxicity.
b. Which lab value to monitor? For diabetic?
i. Monitor blood sugar in diabetics.
c. Can they be pregnant, lactating or not?
i. Cannot be pregnant

Question 14

chloroquine phosphate

Answer 14

a. Used: treat malaria
b. Education: Use condom, avoid raw fish, take it on empty stomach. Have vision exam every 3 months - ototoxicity.
i. Take on empty

Question 15

mebendazole

Answer 15

anthelminitics (worm)

Question 16

permethrin

Answer 16

a. Used: treatment of infestation Scabies and pediculicides

i. lotion only

Question 17

Glyburide

Answer 17

a. For type 2 diabetic
b. Need to have functioning beta cell to use it
d. Assess for jaundice, dark urine, contraindicated in diabetic ketoacidosis

Question 18

Metformin

Answer 18

a. Can crush it but not the XR
b. Can you take it with meal or not?
c. Do not give with acarbose.

Question 19

Propylthiouracil

Answer 19

Anti-thyroid drugs, treat hyperthyroid

i. Can cause hypothyroid

Question 20

Levothyroxine

Answer 20

Treat hypothyroid

a. if given too much, can cause hyperthyroid

Question 21

trimethoprim-sulfamethoxazole

Answer 21

SJS
Renal implication: BUN and Creatinine lab level
hypersensitivity to sulfa drugs
Take at equal interval.
Infuse 60-90 and flush
Monitor for for reaction, no IM. 8-10 glasses of water

Question 22

Red Man Syndrome

Answer 22

Vancomycin

Gentamicin