Antibiotic

Question 1

Protein synthesis inhibitor antibiotics

Answer 1

gentamicin

Question 2

nucleic acid synthesis inhibitor

Answer 2

ciprofloxacin

Question 3

cell wall synthesis inhibitor antibiotic

Answer 3

amoxicillin

Question 4

————&————- have PAEs against Gram -ve bacteria up to 4 hours.

Answer 4

Aminoglycosides (AG)

fluoroquinolones

Question 5

The most beta-lactam (except for————) have no PAEs against G

Answer 5

imipenem

Question 6

Example of Using the combination of antibiotics To achieve synergistic effects ?

Answer 6

Amoxicillin & Gentamicine

Question 7

Example of Using the combination of antibiotics that will cause Drug antagonism:

Answer 7

penicillin plus tetracycline

Question 8

Example of superinfection:

Answer 8

clostridium difficile-associated diarrhea (CDAD)

Question 9

broad-spectrum antibiotics that cause disruption of the normal bacterial flora

Answer 9

clindamycin

Question 10

Complications of CDAD:

Answer 10

watery or bloody diarrhea

pseudomembranous colitis

sepsis

Question 11

Drug of choice for treatment of CDAD:

Answer 11

Metronidazole

Question 12

Example of primary resistance:

Answer 12

methicillin resistant staphylococcus aureus (MRSA) in the hospital

Question 13

persons with antibiotic-resistant:

Answer 13

TB patients with multiple drug

resistance

Question 14

————- interfere with folic acid synthesis

Answer 14

Sulfamethoxazole

Question 15

—————- bacteria increase PABA production

Answer 15

Sulfonamide-resistant

Question 16

Example of Decreasing drug permeability:

Answer 16

aminoglycoside

Question 17

Example of Increasing active efflux (pumping out) of the drugs across the cell surface

Answer 17

tetracycline