Antibiograms & Multidrug resistance infections

Question 1

Methicillin Resistance Staphlococcus Aureus (MRSA) is resistance to ?

Answer 1

• Narrow spectrum natural penicilins

- Often Aminoglycosides

Question 2

How is MRSA resistance conferred by?

Answer 2

• Plasmid that encodes an alternate transpeptidase that does not bind most penicillins

Question 3

T or F

Antibiotic resistance varies across the Country, across counties, across local hospitals/clinics, and time?

Answer 3

• True

Question 4

What is an antibiogram?

Answer 4

• Monitors antibiotic resistance
• Survey of antibiotic resistance (Clinical isolates) Hospitals and Clinics
• Safest way to gamble on Antibiotics

Question 5

Purpose of an Antibiogram?

Answer 5

• Allows clinicians to make educated guesses on Antibiotic selection
• Empiric therapy
• Definitive therapy

Question 6

Goal of managing antibiotic resistant infections?

Answer 6

• Knowledge of Pharmacology
• Patient background
• Antibiogram
• References (ePocrates, UpToDate)