Antibacterial Agents Spectrum Flashcards
G+ cocci
Streptococcus pneumoniae > pneumonia, otitis media, sinusitis
Pen G, Pen V Amoxicillin Vancomycin Cefepime (4th) Macrolides Clindamycin Linezolid Quinupristin / Dalfopristin
G+ cocci
Streptococcus pyogenes > pharyngitis
Macrolides
Clindamycin
G+ cocci
“Viridans” Streptococci > endocarditis
Vancomycin
G+ cocci Staphylococcus aureus (MSSA-MRSA) > cutaneous infection, pneumonia, bacteremia, device associated infections
MSSA: Oxacillin, Cephalexin (1st), Cefazolin (1st), Clindamycin
MRSA: NO Penicillins, Vancomycin, Clindamycin
Doxycycline (Tetracycline)
Linezolid
Quinupristin / Dalfopristin
G+ cocci
Enterococcus faecium-faecalis > bacteremia, intraabdominal infections, urinary tract infections
bacteremia: Pen G, Ampicillin UTI: Ampicillin Aminoglycosides Linezolid Quinupristin / Dalfopristin
G- cocci
Neisseria gonorrheae > gonorrhea
Pen G (though high levels of resistance)
G- rod
E. coli > UTIs, intra-abdominal infections, lower respiratory infections, bacteremias, traveler’s diarrhea
Ampicillin, Amoxicillin +/- Clavulanate Cephalexin (1st) Cefotaxime (3rd), Ceftriaxone (3rd) Cefepime (4th) Carbapenems Aminoglycosides
G- rod
H. influenza > meningitis, otitis media, sinusitis, community-acquired pneumonia
Ampicillin, Amoxicillin +/- Clavulanate Cefuroxime (2nd), Cefaclor (2nd) Cefotaxime (3rd) Azithromycin, Clarithromycin (Macrolides) Doxycycline (Tetracycline)
G- rod
Klebsiella > urinary tract infections, intra-abdominal infections, lower respiratory infections, bacteremias
Ampicillin, Amoxicillin +/- Clavulanate
Cephalexin (1st)
Cefepime (4th)
Aminoglycosides
G- rod
Pseudomonas aeruginosa > nosocomial infections at any site (urinary tract infections, pneumonia)
Ampicillin, Amoxicillin +/- Clavulanate Ceftazidime (3rd) Cefepime (4th) Carbapenems Aminoglycosides
Anaerobes G+ rod
Clostridium difficile > pseudomembranous colitis
Vancomycin
Anaerobes G+ rod
Clostridium perfringens-botulinum-tetani
Pen G
Carbapenems
Clindamycin
Anaerobes G- rod
Bacteroides fragilis > intraabdominal and brain abscess
Piperacillin - Tazobactam, Ticarcillin - Clavulanate Cefoxitin (2nd) Carbapenems Clindamycin Chloramphenicol (brain)
Atypical
Chlamydia > trachoma, community-acquired pneumonia, urethitis
Azithromycin (Macrolide)
Doxycycline (Tetracycline)
Atypical
Mycoplasma pneumoniae > community-acquired pneumonia
Macrolides
Doxycycline (Tetracycline)