Antibacterial Agents Flashcards
What is the drug of choice for acute otitis media, H Pylori and endocarditis?
amox/clav (Augmentin)
Does Augmentin need to be refrigerated?
Yes refrigerate, the suspension is ok at room temperature for 14 days
What is the dose of amoxicillin?
take every 8-12 hours with or without food
Which penicillins cover Pseudomonas?
- ticarcillin/clavulanic (Timentin)
- piperacillin/tazobactam (Zosyn)
How do penicillins affects birth control?
decrease effectiveness of birth control
What are your Penicillin G Salts and how are they given?
(K,procaine,benzathine) are given by deep IM Injection
What are your extended spectrum penicillins
- nafcillin (Nafcil,Nallpen) IV
-oxacillin (Bactocilli) IV
- dicloxacillin (Dynapen) oral
What are your extended spectrum penicillins used for?
- MSSA (strep)
- skin and soft tissue infections
- endocarditis
- bone and joint infections
How do Pencillins affect your kidneys and what pregnancy category are they?
- category B
- can lead to renal toxicity because they are really metabolized
What are your first generation cephalosporins
- cefadroxil (Duricef)
- cefazolin (Ancef,Kefzol)
- cephalexin (Keflex)
What types of infections are first generation cephalosporins normally used for?
- gram positive skin and soft tissue infections
What are your second generation cephalosporins?
- cefoxitin (Mefoxin)
- cefprozil (Cefzil)
- cefaclor (Ceclor)
- cefuroxime (Ceftin,Zinacef)
What types of infections are second generation cephalosporins normally used for?
- gram positive and negative respiratory infections
What are your third generation cephalosporins aka Streptococcal cephalosporins?
- cefdinir (Omnicef)
- ceftazidime (Fortaz)
- ceftriaxone (Rocephin)
- cefotaxime (Claforan)
- cefixime (Suprax)
What are your 4th generation cephalosporins and what do they cover that others do not?
- cefepime (Maxipime)
- these cover pseudomonas
What are your fifth generation cephalosporins and what do they cover?
ceftaroline (Teflaro)
- these do cover MRSA
Do you need to dose adjust cephalosporins per kidney function?
- yes but if their CRCL is greater than 50 do not dose adjust
What is the cross sensitivity that cephalosporins have with the penicillins?
- they have a 1% cross sensitivity with Pencillins if this is a concern you should use >/= third generation cephalosporins
Which special cephalosporins are given from intra-abdominal infections and UTIs?
What is the drug Fetroja?
What are your main carbapenems and what do they cover?
Do carbapenems need to be really adjusted? What pregnancy category are they?
What are your monobactams and what do they cover?
What are your macrolides and what do they cover?
What are the key points about the macrolide telithromycin?
The suspension forms of these macrolides should not be refrigerated?
The suspension form of this macrolide needs to be refrigerated?
How do macrolides affected pregnancy?
What is the main lincosamide? What is its black box warning and does it need to be refrigerated?
What do the fluroroquinolones cover? Do you need to refrigerator them do you need to take with or without food?
What are your main fluoroquinolone?
What are the main side effects of fluroquinolones?
Do you need to dose adjust fluroroquinolones in renal impairment?
What are your main Tetracyclines and what are they used for?
What is important to remember with regards to what to take with tetracyclines?
What are the main side effects of tetracyclines?
What is Synercid used for?
What is daptomycin used for?
What is telavancin used for?
What is linezolid used for?
what is metronidazole used for?
What are the side effects of metronidazole?
What are your main aminoglycosides and what are they used for?
What are the main side effects fro aminoglycosides?
What are the main side effects of vancomycin?
What is vancomycin used for?
What is chloramphenicol used for?
