Antibacterial agents Flashcards
What are antibacterial agents for?
- Therapeutic
- Prophylactic
What does aminoglycoides, phenicols, tetracyclines and lincosamides do to inhibit protein synthesis?
- Broad spectrum
What does macrocodes do to inhibit protein synthesis?
- Narrows spectrum
What does procaine penicillin, amoxcillin and cephalexin do to inhibit cell wall synthesis?
- Broad and narrow spectrum
What does glycolpeprides do to inhibit cell wall synthesis?
- Narrow spectrum
What does nitoimidazoles and fluoroquinolones do to inhibit DNA synthesis and replication?
- Narrow and broad spectrum
What does rifamycin do to inhibit DNA synthesis and replication?
- Broad spectrum
What does sulphonamides and diaminopyramidines do to inhibit folic acid>no DNA synthesis?
- Broad spectrum
What does polymyxins do to impair cell membrane function?
- Narrow spectrum
What are antibiotic side effects?
- Diarrhoea
- Vomiting
- Hypersensitivity reactions
- Nephrotoxicity (gentamycin)
- Superinfection
- Fungal infection
What types of antibiotic resistance is there?
- Intrinsic/inherent resistance
- Acquired resistance
- Multi-drug resistance
What are the types of bacteria that are hard to kill?
- E.Coli
- MRSP
- Klebsiella
- MRSA
- C.Diff
- Enterococcus
What are the types of antifungal agent drugs?
- Griseofulvin
- Nystatin
- Azoles
What are the types of antiprotozoal agent drugs?
- Triazines
