Antiarrhythmics Flashcards
1
Q
Name the Class III Agents.
A
K+ channel blocker
AMiodarone, Dronedarone, Sotalol
2
Q
What is Amio used for?
A
- 1st line for vfib/vtach if no defib
- treat any dyshrthmia except torsades (Class I/II/III/IV propteries)
3
Q
What is the dose for Amio?
A
150-300 mg IV bolus
1 mg/hr x 6 hrs
0.5 mg/hr x 18 hrs
4
Q
Does amio have active/nonactive metabolite?
A
active
5
Q
What kind of binding does amio have?
A
extensive protein
6
Q
Adv effects of amio
A
pulm toxicity - pneumonitis, fibrosis, pulm edema
proarrhythmic
heartblock
hypotension
7
Q
What effect does amio have on other drugs?
A
CP450 INHIBITOR - dec warfarin/digoxin clearance
