Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

BLOCK 1 DRUGS > Antiarrhythmic Agents > Flashcards

Antiarrhythmic Agents Flashcards

1
Q

List the Class 1A: Na+ Channel Blockers

“Double Quarter Pounder”

A
  • Quinidine
  • Procainamide
  • Disopyramide

“Double Quarter Pounder”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

List the Class 1B: Na+ Channel Blockers

“Mexican lettuce tacos”

A
  • Lidocaine
  • Tocainide
  • Mexiletine

“Mexican lettuce tacos”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

List the Class 1C: Na+ Channel Blockers

“Purple motorola flip phone”

A
  • Flecainide
  • Propafenone
  • Moricizine

“Purple motorola flip phone”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Class 1A: Na+ Channel Blockers…

______ Vmax & ________ APD

A

↓ Vmax & Prolonged APD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Class 1B: Na+ Channel Blockers…

______ Vmax & ________ APD

A

NO EFFECT on Vmax & SHORTENED APD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Class 1C: Na+ Channel Blockers…

______ Vmax & ________ APD

A

Significantly ↓
Vmax & NO EFFECT
APD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the adverse effects of QUINIDINE? (4)

A
  1. Cinchonism
  2. ↑ QT interval (Torsades)
  3. Displaces digoxin from tissue binding sites
  4. Antacids will increase its absorption and toxicities
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which drug has the side effect of tinnitus, loss of hearing, GI upset, and diplopia?

A

QUINIDINE

Class 1: Na+ Channel Blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which drug has the side effect with the use of antacids causing an ↑ in toxicities?

A

QUINIDINE

Class 1: Na+ Channel Blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which drug has the side effect of *Agranulocytosis *

↓ WBC

A

PROCAINAMIDE

Class 1: Na+ Channel Blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which drug has the side effect of SLE like syndrome?

A

PROCAINAMIDE

Class 1: Na+ Channel Blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the least anticholinergic Class 1: Na+ Channel Blocking Drug?

A

PROCAINAMIDE

Active metabolite NAPA (N-Acetyl procainamide)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the most anticholinergic Class 1: Na+ Channel Blocking Drug?

A

DISOPYRAMIDE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What two effects take place in the drug QUINIDINE?

A
  1. Anticholinergic Effect
  2. Alpha Blocking Effect
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the action of the anticholinergic effect in the drug QUINIDINE?

A

Anticholinergic Effect: ↑ heart rate & conductance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the action of the alpha blocking effect in the drug QUINIDINE?

A

Alpha Blocking Effect: Vasodilation & Reflex Tachycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which class of drugs increases the threshold for Vfib?

(more protective effect)

A

Class 1B: Na+ Channel Blocking Drug

  • Lidocaine
  • Mexiletine
  • Tocainide
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Which Class 1B: Na+ Channel Blocking Drug is the least cardiotoxic?

A

LIDOCAINE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are the adverse effects of LIDOCAINE? (3)

CLASS 1B: Na+ Channel Blocker

A
  • Drowsiness
  • Paresthesia
  • Convulsions
20
Q

Are the drugs MEXILETINE & TOCAINIDE given IV or orally?

CLASS 1B: Na+ Channel Blocker

A

ORALLY

LIDOCAINE is given IV

21
Q

Which class of drugs works on both the activated & inactivated Na+ channels?

A

Class 1C: Na+ Channel Blocking Drugs

  • Flecainide
  • Propafenone
  • Moricizine
22
Q

Which class of drugs are used for life threatening Vtach & Vfib?

Also used for Refractory SVT

A

Class 1C: Na+ Channel Blocking Drugs

  • Flecainide
  • Propafenone
  • Moricizine
23
Q

What are the adverse effects of Class 1C: Na+ Channel Blocking Drugs?

A
  1. Proarrhythimic Effect
  2. ↑ sudden death & cardiac arrest via decrease in LV function after an MI
24
Q

What is the drug of choice for SVT/PSVT in emergency situations?

A

ADENOSINE

25
Q

What are the adverse side effects of adenosine? (3)

A
  • Flushing
  • SOB
  • Burning sensation in the chest
26
Q

Which drug has the following adverse side effects: flushing, shortness of breath, and burning in the chest?

A

ADENOSINE

27
Q

What are the 2 clinical uses for DIGOXIN?

A
  1. Heart Failure
  2. Control ventricular rates in afib & aflutter
28
Q

List the drugs that are capable of causing Torsades de Pointes. (5)

A
  1. AMIODARONE
  2. QUINIDINE
  3. SOTALOL
  4. THIORIDAZINE
  5. TRICYCLIC ANTIDEPRESSANTS
29
Q

List the Class II: Beta Blockers

A
  • Meoprolol
  • Propranolol
  • Acebutolol
  • Esmolol
30
Q

Which class of antiarrhythmics has the mechanism of action of ↓SA & AV nodal conduction?

Also has a decrease in the slope of phase 4 depolarization

A

Class II: Beta Blockers

  • Meoprolol
  • Propranolol
  • Acebutolol
  • Esmolol
31
Q

What’s the adverse effect of Class II: Beta Blockers?

  • Meoprolol
  • Propranolol
  • Acebutolol
  • Esmolol
A

Proarrhythmic: Can cause AV block

prolonged PR interval

32
Q

Which Class II: Beta Blocker is given IV for emergency Rx of SVT?

  • Meoprolol
  • Propranolol
  • Acebutolol
  • Esmolol
A

ESMOLOL

33
Q

What is the clinical use of Class II: Beta Blockers? (2)

  • Meoprolol
  • Propranolol
  • Acebutolol
  • Esmolol
A
  1. Prophylaxis for ventricular arrhythmias Post MI
  2. Rx of SVTs
34
Q

Which class of drugs has the clinical use of :

  1. Prophylaxis for ventricular arrhythmias Post MI
  2. Rx of SVTs
A

Class II: Beta Blockers

  • Meoprolol
  • Propranolol
  • Acebutolol
  • Esmolol
35
Q

Which class of drugs has the clinical use for Atrial Fibrillation & Ventricular Tachycardia?

A

Class 3: K+ Channel Blockers

36
Q

List the Class 3: K+ Channel Blockers.

A
  • Amiodarone
  • Sotalol
  • Dofetilide
  • Ibutilide
  • Dronaderone
37
Q

Which class of drugs does the following:

  • ↑ APD & ERP
  • Prolongs repolarization and lengthen the PLATEAU phase (phase 2)?
A

Class 3: K+ Channel Blockers.

  • Amiodarone
  • Sotalol
  • Dofetilide
  • Ibutilide
  • Dronaderone
38
Q

What are the adverse effects of AMIODARONE?

A
  • Pulmonary Fibrosis
  • Hepatotoxicity
  • Smurf Skin
  • Hypothyroidism & Hypethyroidism
  • Torsades de Pointes
39
Q

Which drug has the adverse effects of pulmonary fibrosis and hepatotoxicity?

A

AMIODARONE

40
Q

Which Class 3: K+ Channel Blocker drugs are used for pharmacological cardioversion of atrial fibrillation and flutter?

A

IBUTILIDE & DOFETILIDE

41
Q

Which drug’s clinical use pertains to atrial fibrillation and life-threatening ventricular arrythmias?

A

SOTALOL

42
Q

Which drug has the following side effects:
- Torsades de Pointes
- Headaches, depression, and impotency
- Issue with asthmatics

A

SOTALOL

Class 3: K+ Channel Blockers

43
Q

List the Class 4: Calcium Channel Blockers

A
  • DILITIAZEM
  • VERAPAMIL
44
Q

Which class of drugs have the clinical use of PSVT due to AV nodal re-entry?

A

Class 4: Calcium Channel Blockers

  • DILITIAZEM
  • VERAPAMIL
45
Q

Which class of drugs contain the adverse effects of orthostatic hypotension and lower extremity edema?

A

Class 4: Calcium Channel Blockers

  • DILITIAZEM
  • VERAPAMIL
46
Q

Which Class 4: Calcium Channel Blocker displaces digoxin and increases its toxicity as a result?

A

VERAPAMIL

47
Q

Which class of drugs has the adverse effect of atrial tachycardia due to WPW?

delta wave

A

Class 4: Calcium Channel Blockers

  • DILITIAZEM
  • VERAPAMIL

BLOCK 1 DRUGS (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions