Anti viral Flashcards
Anti herpes virus
Acyclovir
Valacyclovir
Anti retrovirus agent
zidovudine
Nevirapine
Anti influenza virus
Amantadine
Rimantadine
drugs for Herpes simplex virus 1 and 2
Acyclovir and Valacyclovir
Drugs for varicella zoster virus
Acyclovir, valacyclovir, ganciclovir, valganciclovir
Acyclovir and Valacyclovir
Guanosine analogue
valacyclovir is the pro drug with improved oral bioavailability.
Mechanism:
Acyclovir converted to active metabolite.
inhibits viral DNA polymerase
prevents replication
Uses:
HSV1 and 2, VZV
weak against cytomegalovirus
Anti retroviral drugs
active against HIV
postpones the complication but not cure.
nucleoside reverse transcriptase inhibitors
Zidovudine
non nucleoside reverse transcriptase inhibitors and USES
Nevirapine
USES:
Prevents HIV transmission from mother to newborn.
HAART
HIGHLY ACTIVE ANTI RETROVIRAL THERAPY
2 NRTI + 1 protease inhibitor
2 NRTI + 1 NNRTI