Anti viral Flashcards

1
Q

Anti herpes virus

A

Acyclovir
Valacyclovir

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2
Q

Anti retrovirus agent

A

zidovudine
Nevirapine

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3
Q

Anti influenza virus

A

Amantadine
Rimantadine

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4
Q

drugs for Herpes simplex virus 1 and 2

A

Acyclovir and Valacyclovir

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5
Q

Drugs for varicella zoster virus

A

Acyclovir, valacyclovir, ganciclovir, valganciclovir

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6
Q

Acyclovir and Valacyclovir

A

Guanosine analogue
valacyclovir is the pro drug with improved oral bioavailability.
Mechanism:
Acyclovir converted to active metabolite.
inhibits viral DNA polymerase
prevents replication
Uses:
HSV1 and 2, VZV
weak against cytomegalovirus

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7
Q

Anti retroviral drugs

A

active against HIV
postpones the complication but not cure.

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8
Q

nucleoside reverse transcriptase inhibitors

A

Zidovudine

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9
Q

non nucleoside reverse transcriptase inhibitors and USES

A

Nevirapine
USES:
Prevents HIV transmission from mother to newborn.

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10
Q

HAART

A

HIGHLY ACTIVE ANTI RETROVIRAL THERAPY
2 NRTI + 1 protease inhibitor
2 NRTI + 1 NNRTI

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