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Antibiotics > Anti-tubercular Drug > Flashcards

Anti-tubercular Drug Flashcards

1
Q

Isoniazid

A

Mechanism: decrease synthesis of mycolic acids. Bacterial catalase perioxidase needed
Toxicity: Neurotoxcity, hepatoxicity

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2
Q

Rifamycin

A

Mechanism: Inhibits DNA-dependent RNA polymerase

Side Effect: hepatitis, induction of cyp450, red orange metabolite

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3
Q

Ethambutol

A

Mechanism: Inhibits synthesis of arabingalactan (cell wall component)
side Effect: Dose dependent retorbulbar neuritis

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4
Q

Pyrazinamide

A

Mechanism: unknown

Side Effect: Hepatitis, Hyperuricemia

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Antibiotics (4 decks)

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