Anti-thrombotiques Flashcards

1
Q

HNF: dose curative

A

Bolus de 50UI/kg

15UI/kg/h ou 500UI/kg/24h IVSE

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2
Q

HNF contre-indications

A

Allergie
Atcd de TIH
Risque hemorragique
Endocardite infectieuse

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3
Q

HNF: surveillance

A

TCA 6h (ou 4/3 si SC) puis quotidien
Plaquettes 2x/semaine
Héparinémie si TCA non fiable

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4
Q

DCI du Lovenox

A

Enoxaparine

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5
Q

Lovenox: dose préventive

A

Risque élevé: 4000 UI/j

Risque faible: 2000 UI/j

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6
Q

Lovenox: dose curative

A

2 x 100UI/kg/j

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7
Q

Citer 2 HBPM: nom commercial et DCI

A

Lovenox - Enoxaparine

Innohep - Tinzaparine

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8
Q

Contre-indications des HBPM

A

Insuffisance rénale + contre-indications de l’HNF

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9
Q

Fondaparinux - Arixtra: dose préventive

A

2,5mg/kg/j

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10
Q

Fondaparinux - Arixtra: dose curative

A

7,5mg/kg/j

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11
Q

Contre-indication des pentasaccharides

A

Insuffisance rénale

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12
Q

Surveillance des HBPM

A

Plaquettes 2 fois par semaine

Poids extrèmes ou insuffisance rénale: activite anti-Xa

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13
Q

Surveillance des pentsaccharides

A

Aucune

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14
Q

Héparine: dose préventive

A

5000 UI toutes les 12h

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