anti-platelet drugs Flashcards

1
Q

Aspirin

A
  • Acetyl salicylic acid
  • inhibit formation of PGH2, leading to inhibit TXA2 & PGI2
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2
Q

Clopidogrel

A

Plavix

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3
Q

Prasugrel

A

Effient

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4
Q

Ticagrelor

A

Brilinta

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5
Q

Vorapaxar

A

Zontivity

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6
Q

Abciximab

A

Reopro

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7
Q

Tirofiban

A

Aggrastat

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8
Q

Eptifibatide

A

Integrilin

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9
Q

Dipyridamole

A

increase cAMP

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10
Q

Cilostazol

A

PDE3 inhibitor
- raise cAMP leading to anti aggregation effect and reduce chance of clotting

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11
Q

Pentoxifyline

A
  • doesn’t affect platelet
  • affects RBC -> change shape (rheological modifier)
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12
Q

Anagrelide

A

PDE3 inhibitor
- inhibit maturation of megakaryocyte
- used for thrombocythemia

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