Anti platelet / Anti coagulation

Question 1

Interfere with Vit K carboxylation

Answer 1

Warfarin

Question 2

activate antithrombin

Answer 2

Heparin
LMW heparins (enoxaparin, dalteparin, fondaparinux

Question 3

directly inhibit Xa

Answer 3

Apixaban, rivaroxaban

Question 4

convert plasminogen to plasmin

Answer 4

Alteplase (tap)

Question 5

inhibit both cox 1 and cox 2

Answer 5

aspirin

Question 6

inhibit ADP receptors (prevents plt aggregation)

Answer 6

clopidogrel
prasugrel
ticagrelor
ticlopidine

Question 7

block phosphodiesterase III; increase cAMP (prevents plt aggregation)

Answer 7

cilostazol, dipyridamole

Question 8

GP IIb/IIIa inhibitors

Answer 8

Abciximab
eptifibatide
tirofiban

Question 9

MOA

Clopidogrel

Answer 9

ADP receptor inhibitor

Question 10

MOA

Ticegrelor

Answer 10

reversible ADP receptor inhibitor

Question 11

MOA

cilostazol

Answer 11

phosphodiesterase III inhibitor ; increases cAMP

Question 12

MOA

Abciximab

Answer 12

fab fragment blocks GP IIb/III a

plt aggregation

Question 13

MOA

rivaroxaban

Answer 13

direct Xa inhibitor

Question 14

MOA

Argatroban

Answer 14

inhibit thrombin directly

Question 15

Direct thrombin inhibitors

Answer 15

Argatroban,
bivalirudin
dabigatran

Question 16

Pt has Heparin induced thrombocytopenia

what substitute is used to prevent thrombosis

Answer 16

argatroban

alternatives for heparin