anti muscarinic drugs

Question 1

ipratropium, tiotropium and glycoperonium are atropine substitues because:

Answer 1

1. they are more selective 2. decrease mucus secretion
2. increase mucociliary clearance
3. do not cross BBB

Question 2

tiotropium

Answer 2

selective m3 receptor blocker so no tolerance is formed, 2. good fro COPD patients and decrease their exacerbations

Question 3

ipratropium

Answer 3

not recommended alone because its onset is slower than SABAs