Anti-microbials by Disease

Question 1

Strep Throat

Answer 1

Pen V
Pen G (with Procaine or Benzathine)
Cephalexin
Erythromycin

Question 2

Staph (MSSA)

Answer 2

Oxacillin
Amoxicillin + Clavulanate
Linezolid
Cefazolin, Cephalexin
Erythromycin
Daptomycin

Question 3

Staph (HA-MRSA)

Answer 3

Vancomycin
Linezolid
Daptomycin
Tigecycline

Question 4

Gonorrhea

Answer 4

Ceftriaxone + Azithromycin

Doxycycline

Question 5

Chlamydia

Answer 5

Azithromycin
Doxycycline
Ciprofloxacin
Norifloxacin

Question 6

Syphilis

Answer 6

Pen G benzathine

Minocycline, doxycycline

Question 7

UTI Empiric

Answer 7

TMP/SMX (E. coli, Staph)
Nitrofurantoin (E. coli, Staph, Enterococcus)
Fosfomycin (E. coli, Enterococcus)
Norfloxacin
Ciprofloxacin

Question 8

Strict Anaerobes (Gram +/-)

Answer 8

Metronidazole
Tigecycline
Cefoxitin
Amoxicillin + Clavulanate
Ticarcillin + Clavulanate
Clindamycin
Imipenem + Cilastatin
Chloramphenicol

Question 9

Strict Anaerobes (Gram +)

Answer 9

Pen G
Vancomycin
Daptomycin

Question 10

Middle Ear Infections (Empiric)

Answer 10

Amoxicillin
Azithromycin
TMP/SMX
Cefuroxime

Question 11

Bacterial Meningitis (Empiric)

Answer 11

Ceftriaxone + Vancomycin

Question 12

Lyme Disease

Answer 12

Doxycycline
Amoxicillin
Ceftriaxone
Pen G

Question 13

Gram-negs (E. Coli, Klevsiella)

Answer 13

Tigecycline
Piperacillin + Tazobactam
Ceftriaxone
Ceftazidime
Cefepime
Aztreonam
Imipenem
Tobramycin, Amikacin
Polymyxin B (Topical)

Question 14

Pseudomonas

Answer 14

Piperacillin + Tazobactam
Ceftazidime
Cefepime
Aztreonam
Imipenem
Tobramycin, Amikacin
Polymyxin B

Question 15

ESBL-Positive Gram-Negs

Answer 15

Imipenem

Question 16

Surgical prophylaxis against skin flora

Answer 16

Cefazolin

Question 17

C. difficile Enterocolitis

Answer 17

Metronidazole
Vancomycin
Fidaxomicin

Question 18

Gastric ulcers (H. pylori)

Answer 18

Pick 2 Antibiotics:
Clarithromycin
Metronidazole
Amoxicillin
Tetracycline

Pick 1 PPi:
Omeprazole
Ranitidine

Question 19

Atypical Pneumonia Pathogens (Community-acquired)

Answer 19

Azithromycin
Doxycycline (Not Legionella)
Moxifloxacin

Question 20

Tuberculosis

Answer 20

Isoniazid
Rifampin
Ethambutol
Pyrazinamide
Streptomycin

Question 21

MAC

Answer 21

Rifabutin

Clarithromycin

Question 22

Leprosy

Answer 22

Dapsone
Clofazimine
Rifampin

Question 23

Candida

Answer 23

Flucytosine (Systemic)
Fluconazole
Itraconazole (Systemic Not CNS & UTI, Oropharyngeal, Esophageal)
Voriconazole (Systemic, Not UTI)
Caspofungin (Esophageal and systemic)
Miconazole (Vaginal)
Clotrimazole (Topical for oral troches or vaginal)
Nystatin (Topical, Azole-resistant strains)

Question 24

Cryptococcus

Answer 24

Flucytosine

Fluconazole

Question 25

Blastomyces

Answer 25

Itraconazole

Question 26

Histoplasma

Answer 26

Itraconazole

Question 27

Aspergillus

Answer 27

Voriconazole | Caspofungin

Question 28

Fusarium

Answer 28

Voriconazole

Question 29

Scedosporium

Answer 29

Voriconazole

Question 30

Dermatophytes

Answer 30

``` Ciclopirox (Nail) Terbinafine (Nail) Griseofulvin (Skin, Hair, Nails) Itraconazole (Toenail) Miconazole, Clotrimazole Tolnaftate ```

Question 31

Community-Acquired MRSA

Answer 31

Linezolid Doxycycline, Minocycline Clindamycin TMP-SMX

Question 32

Intestinal Roundworms

Answer 32

Mebendazole

Question 33

Echinococcus

Answer 33

Albendazole

Question 34

Strongyloides

Answer 34

Thiabendazole

Question 35

Cutaneous larval migrans

Answer 35

Albendazole, Thiabendazole

Question 36

Hookworm, Pinworm, and Roundworm

Answer 36

Pyrantel Pamoate

Question 37

Schistosoma (Trematodes)

Answer 37

Praziquantel

Question 38

Cestodes

Answer 38

Praziquantel (Esp. Taenia solium) Albendazole (Neurocysticercosis) Paromomycin sulfate (3rd Chance)

Question 39

P. falciparium

Answer 39

``` Chloroquine Mefloquine Atovaquone + Proguanil Quinine Doxycycline ```

Question 40

P. vivax

Answer 40

Chloroquine Mefloquine Primaquine Quinine

Question 41

P. ovale

Answer 41

Chloroquine Quinine Primaquine

Question 42

P. malariae

Answer 42

Chloroquine | Quinine

Question 43

Tissue Amoeba

Answer 43

Metronidazole

Question 44

Luminal Amoeba

Answer 44

Iodoquinol | Paromomycin Sulfate

Question 45

Giardia lamblia

Answer 45

Metronidazole (Drug of choice) | Nitazoxanide

Question 46

Trichomonas vaginalis

Answer 46

Metronidazole

Question 47

Cryptosporidium parvum

Answer 47

Nitazoxanide

Question 48

Toxoplasma gondii

Answer 48

Atovaquone

Question 49

Pneumocystis jiroveci

Answer 49

TMP-SMX Clindamycin + Primaquine Atovaquone Dapsone

Question 50

Influenza

Answer 50

Amantadine (A) | Oseltamivir (A/B)

Question 51

HSV

Answer 51

Eye - Trifluridine Lips/face - Penciclovir, Acyclovir Genital - Acyclovir, Famciclovir Acyclovir-resistant - Foscarnet

Question 52

Herpes Zoster

Answer 52

Famciclovir

Question 53

CMV

Answer 53

Ganciclovir | Foscarnet

Question 54

RSV

Answer 54

Ribavirin

Question 55

HBV

Answer 55

Lamivudine + Interferon A + Tenofovir

Question 56

HCV

Answer 56

Ribavirin + Interferon A + Boceprevir

Question 57

HIV

Answer 57

``` NRTI: Zidovudine Lamivudine Tenofovir Emtricitabine Abacavir ``` NNRTI: Efavirenz Protease inhibitor: Lopinavir + Ritonavir Fusion inhibitors: Enfuvirtide CCR5 antagonist Maraviroc Integrase: Raltegravir