Anti lipemic agent

Question 1

what are the names of cholesterol absorption inhibitors

Answer 1

Ezetimibe

Question 2

what is the pharmacolgical action of Cholesterol absorption inhibitors

Answer 2

they inhibit absorption of cholesterol secreted in the bile and from food

Question 3

what are the uses

Answer 3

pts with a modified diet use it to help lower LDL cholesterol, this medication can be used alone or with a statin

Question 4

What other med can this drug be combined with

Answer 4

may be used alone or with a statin

Question 5

what are the known complications or side effects from this drug ?

Answer 5

Myopathy , hepatitis

Question 6

to monitor for hepatitis in a pt they will show

Answer 6

anorexia , nausea , vomiting jaundice

Question 7

labs to monitor are

Answer 7

liver function , and ck levels

Question 8

Pregnancy risk category

Answer 8

x

Question 9

Contraindicated i

Answer 9

moderate to sever liver disorders

Question 10

interaction with Bile acid sequestrants

Answer 10

advise clients to take ezetimibe 1 hr before or 4 hr after taking sequestrants

Question 11

ezetimibe is not recommended with use of

Answer 11

fibrates, such as gemfibrozil increase the risk for cholelithiasis and myopathy

Question 12

Levles of ezetimibe become increased when taken along with

Answer 12

cyclosporine

Question 13

Pt is to follow what kind of diet ?

Answer 13

a low fat low cholesterol diet

Question 14

overall labs

Answer 14

baseline : HDL LDL and triglyceride levels liver kidney function

Question 15

Cholesterol absorption inhibitors - Ezetimibe should be taken

Answer 15

30 min before meals