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Respiratory Drugs > anti-inflamatory resp > Flashcards

anti-inflamatory resp Flashcards

1
Q

What are the mast cell stabilizers

A

CromolynNedocromil

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2
Q

What inhaled steroids are used for chronic asthma

A

BeclomethasoneFlunisolide Fluticasone Budesonide

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3
Q

What are the IV steroids

A

DexamethasonePrednisoloneHydrocortisone

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4
Q

Which LT antagonist inhibits LOX

A

Zileuton

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5
Q

Which LT antagonist are LTD4 antagonists

A

ZafirlukastMontelukast

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6
Q

Which resp drug is an antibody

A

Omalizumab

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7
Q

What are the opiods

A

CodeineDextromethorphan

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8
Q

What is the Mycolytic agent

A

N-acetylcysteine (NAC)

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9
Q

1st gen H1 antagonists

A

DiphenhydramineChlorpheniramine

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10
Q

2nd gen H1 antagonists

A

LoratadineFexofenadineCetirizine

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11
Q

What are the alpha agonists

A

PhenylephrinePseudoephedrine

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12
Q

What is the action of adrenergic agonists

A

Increase cAMPBronchial SM relaxation

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13
Q

How do corticosteroids act

A

Inhibit PLA2Bind glucose response elements

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14
Q

When are inhaled steroids given

A

Maintain inflammation supression

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15
Q

Given for severe attacks (status asthmaticus)

A

Systemic steroids

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16
Q

What can be used to treat chronic rhinitis

A

BeclomethasoneFlunisolide

17
Q

Inhaled corticosteroid AE

A

CoughOral thrushDysphonia

18
Q

IV steroid AE

A

Abnormal glucose metabIncrease appetite and weight gainHTNAdrenal supression

19
Q

How do LT antagonists act

A

Block LT synth or LT receptorsDecrease constriction and inflammation

20
Q

When do you give LT antagonists

A

Exercise, Ag, or Aspirin-induced asthmaChronic maintenance

21
Q

What are LT antagonists NOT useful for

A

Acute bronchospasm

22
Q

Zileuton AE

A

Increase LFTs

23
Q

Lukast AE

A

Vasculitis with EOS (similar to Churg-Strauss)

24
Q

How does Omalizumab work

A

Bind IgE on sensitized mast cellsPrevent mediator release

25
Q

When do you give Omalizumab

A

Asthma prophylaxis when inhaled corticosteroids don’t worh (> 12yrs age)

26
Q

What is the AE for Omalizumab

A

Anaphylaxis

27
Q

What is the effect of prolonged alpha agonist use

A

Rebound nasal congestion after discontinuation

Respiratory Drugs (3 decks)

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