anti-inflamatory resp Flashcards
What are the mast cell stabilizers
CromolynNedocromil
What inhaled steroids are used for chronic asthma
BeclomethasoneFlunisolide Fluticasone Budesonide
What are the IV steroids
DexamethasonePrednisoloneHydrocortisone
Which LT antagonist inhibits LOX
Zileuton
Which LT antagonist are LTD4 antagonists
ZafirlukastMontelukast
Which resp drug is an antibody
Omalizumab
What are the opiods
CodeineDextromethorphan
What is the Mycolytic agent
N-acetylcysteine (NAC)
1st gen H1 antagonists
DiphenhydramineChlorpheniramine
2nd gen H1 antagonists
LoratadineFexofenadineCetirizine
What are the alpha agonists
PhenylephrinePseudoephedrine
What is the action of adrenergic agonists
Increase cAMPBronchial SM relaxation
How do corticosteroids act
Inhibit PLA2Bind glucose response elements
When are inhaled steroids given
Maintain inflammation supression
Given for severe attacks (status asthmaticus)
Systemic steroids
What can be used to treat chronic rhinitis
BeclomethasoneFlunisolide
Inhaled corticosteroid AE
CoughOral thrushDysphonia
IV steroid AE
Abnormal glucose metabIncrease appetite and weight gainHTNAdrenal supression
How do LT antagonists act
Block LT synth or LT receptorsDecrease constriction and inflammation
When do you give LT antagonists
Exercise, Ag, or Aspirin-induced asthmaChronic maintenance
What are LT antagonists NOT useful for
Acute bronchospasm
Zileuton AE
Increase LFTs
Lukast AE
Vasculitis with EOS (similar to Churg-Strauss)
How does Omalizumab work
Bind IgE on sensitized mast cellsPrevent mediator release