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Anti-infective Drugs (Antifungal, antiprotozoal) > Anti-infective Drugs (Antifungal, antiprotozoal) > Flashcards

Anti-infective Drugs (Antifungal, antiprotozoal) Flashcards

1
Q

Mycosis

A

Fungal infection (opportunistic infections)

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2
Q

Protozoa

A

Reproduce: crowded places, unsanitary

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3
Q

Azoles

A

Treat: candidiasis, cryptococcosis, histoplasmosis

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4
Q

Malaria

A

Protozoan disease, Incubation period 10-35 days

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5
Q

Metronidazole (Flagyl) & Tinidazole

A

Inhibit DNA synthesis

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6
Q

Nystatin (Mycostatin)

A

Increases permeability of fungal cell membrane

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7
Q

Antimetabolites

A

Used in combination (azole or nystatin) - increases effectiveness and toxicity

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8
Q

Metronidazole (Flagyl) Safety precautions

A

Change in LOC; dizziness

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9
Q

When taking Metronidazole (Flagyl), avoid what?

A

Avoid alcohol and avoid taking during 1st trimester of pregnancy

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10
Q

Benznidazole

A

Used to treat Chagas disease (caused by a parasite) in children 2 to 12 years old.

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11
Q

Fenbendazole

A

Used as an antiparasitic agent against various gastrointestinal parasites

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12
Q

Iodoquinol

A

Inhibits invading organisms from using substances essential to their growth and development

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13
Q

Antifungal agents

A

Kills or inactivates fungi and are used to treat fungal infections

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14
Q

Echinocandins

A

A class of antifungal drugs that target the fungal cell wall

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15
Q

Polyene antifungals

A

Increases the membrane permeability and leads to cell death

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16
Q

Voriconazole

A

Inhibits cytochrome p450 dependent synthesis of ergosterol

17
Q

Atovaquone

A

May interfere with electron transport in protozoal mitochondria

18
Q

Ketoconazole

A

Inhibits yeast growth by altering permeability of cell membrane

19
Q

Carbapenems

A

Inhibits bacterial cell wall synthesis by binding to the penicillin-binding proteins and interfering with cell wall formation

20
Q

Tetracyclines

A

Inhibit protein synthesis in the microbial RNA

21
Q

Leprostatics

A

Inhibit the growth of Mycobacterium leprae, the bacterium that causes leprosy

22
Q

Amphotericin B

A

Treatment of severe fungal infections

23
Q

Amphotericin B

A

Route: IV over 2-6 hours

24
Q

Amphotericin B nursing intv.

A

Monitor vital signs q30 min, give IV slowly

25
Q

Antiprotozoals

A

Atovaquone (Mepron)

26
Q

Clotrimazole

A

Used to treat skin infections such as athlete’s foot

27
Q

Nifuratel

A

Indicated for the treatment of vulvovaginal and urinary tract infections

28
Q

Tinidazole

A

Used to treat infections caused by protozoa

29
Q

Prophylactic Measures for malaria

A

Use long sleeves, go out before dusk

30
Q

Nystatin (Mycostatin) client teaching

A

Swish and swallow

Anti-infective Drugs (Antifungal, antiprotozoal) (1 decks)

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