Anti-infective

Question 1

Flagyl (ER) [generic name]

Answer 1

Metronidazole

Question 2

Flagyl (ER)[drug class]

Answer 2

Anaerobic antibacterial, antiprotozoal

Question 3

Flagyl (ER)[counseling points]

Answer 3

Finish course as prescribed. Avoid ETOH and “hidden” ETOH during therapy and for 72 hours after or may cause “disulfiram type reaction.”. May discolor urine reddish-brown. Most likely can cause nausea, headache, dizziness and metallic taste. Take with food to decrease nausea. Monitor for peripheral neuropathy, seizure activity and mental status changes especially in those with existing conditions and with long and high drug exposure. Do not use in the 1st trimester of pregnancy per FDA. Commonly used for “Trich” and “BV” and anerobic abscess infections

Question 4

Diflucan [generic name]

Answer 4

Fluconazole

Question 5

Diflucan [drug class]

Answer 5

antifungal

Question 6

Diflucan [counseling points]

Answer 6

Finish course as prescribed. May cause headache and GI upset. CYP interactions: strongly inhibits CYP2C19 (ex. Clopidogrel, warfarin and phenytoin) -; moderately inhibits CYP2C9 and 3A4. Even a single dose may lead to toxicity in higher risk meds (simvastatin, lovastatin, S.U,warfarin - especially in the elderly). May prolong QT interval. May cause LFT elevations. 2016 safety alert regarding use in pregnancy and possible complications.

Question 7

Zovirax [generic name]

Answer 7

acyclovir

Question 8

Zovirax [drug class]

Answer 8

antiviral against HSV

Question 9

Zovirax [counseling points]

Answer 9

Finish course as prescribed. May cause headache and GI upset. CYP interactions: strongly inhibits CYP2C19 (ex. Clopidogrel, warfarin and phenytoin) -; moderately inhibits CYP2C9 and 3A4. Even a single dose may lead to toxicity in higher risk meds (simvastatin, lovastatin, S.U,warfarin - especially in the elderly). May prolong QT interval. May cause LFT elevations. 2016 safety alert regarding use in pregnancy and possible complications.

Question 10

Valtrex [generic name]

Answer 10

valacyclovir

Question 11

Valtrex [drug class]

Answer 11

antiviral against HSV

Question 12

Valtrex [counseling points]

Answer 12

Pro-drug of acyclovir. Initiate treatment as early as possible to outbreak at least within 72 hours. Avoid intercourse during herpes outbreaks. Dose and duration depends on indication. CNS side-effects especially in elderly and renal impairment. Stay well hydrated.

Question 13

Keflex [generic name]

Answer 13

cephalexin

Question 14

Keflex [drug class]

Answer 14

Cephalosporin antibiotic, 1st generation

Question 15

Keflex [counseling points]

Answer 15

Finish course as prescribed. May cause GI upset. Hypersensitivity reactions may occur if allergic to penicillin and/or other cephalosporins. May decrease absorption of oral contraceptives.

Question 16

Ceftin [generic name]

Answer 16

cefuroxime

Question 17

Ceftin [drug class]

Answer 17

2nd ten of cephalosporin

Question 18

Ceftin [counseling points]

Answer 18

Finish course as prescribed. May cause GI upset. Hypersensitivity reactions may occur if allergic to penicillin and/or other cephalosporins. May decrease absorption of oral contraceptives.

Question 19

Omnicef [generic name]

Answer 19

cefdinir

Question 20

Omnicef [drug class]

Answer 20

3rd generation of cephalosporin

Question 21

Cipro [generic name]

Answer 21

ciprofloxacin

Question 22

Cipro [drug class]

Answer 22

Fluoroquinolone Abx

Question 23

Cipro [counseling points]

Answer 23

Finish course as prescribed. Monitor glucose. Do not take within 2 hours of consuming foods or other products containing di- or trivalent cations (ex. milk, calcium antacids, multivitamins, iron/magnesium and supplements). May cause sun sensitivity and CNS side-effects. FDA requires assessment of risk of QTc prolongation. Black box warning for tendonitis/tendon rupture. Available orally and in ophthalmic and otic suspensions.

Question 24

Levaquin [generic]

Answer 24

levofloxacin

Question 25

Levaquin [dr

Answer 25

Finish course as prescribed. Monitor glucose. Do not take within 2 hours of consuming foods or other products containing di- or trivalent cations (ex. milk, calcium antacids, multivitamins and supplements). Ions bind directly to the drug in the gut preventing absorption. May cause sun sensitivity and CNS side-effects. FDA requires assessment of risk of QTc prolongation. Black box warning for tendonitis/tendon rupture. Available orally and in ophthalmic suspension.

Question 26

Avelox [generic name]

Answer 26

moxifloxacin

Question 27

Avelox [drug class]

Answer 27

fluoroquinolone

Question 28

Levaquin [drug class]

Answer 28

fluoroquinolone

Question 29

Cleocin [generic]

Answer 29

clindamycin

Question 30

Evoclin [generic]

Answer 30

clindamycin

Question 31

Cleocin [drug class]

Answer 31

lincosamide antibiotic

Question 32

Cleocin [counseling points]

Answer 32

Available in many dosage forms (oral, topical, vaginal suppository, powder for suspension) and combination products. Oral therapy may cause C. diff-associated severe diarrhea. Suspension has horrible taste, little flavoring options available.

Question 33

Macrobid [generic]

Answer 33

nitrofurantoin

Question 34

Macrobid [drug class]

Answer 34

nitrofuran abx

Question 35

Macrobid [counseling points]

Answer 35

Used only for UTI’s. Take BID.Take with food to enhance absorption. May cause urine discoloration (dark brown). May cause peripheral neuropathy or pulmonary fibrosis with chronic dosing and with poor CrCl. Shake suspension thoroughly.