Anti-hypertensive drugs Flashcards
Acts in the lungs to prevent ACE from converting Angiotensin I to Angiotensin II. Powerful Vasoconstrictor and stimulator of adolsterone release
Angiotensin-Converting enzyme (ACE) inhibitors
Drugs under Angiotensin-Converting enzyme (ACE) inhibitors
Family name: Pril
-Benazepril
-Captopril
-enalapril
-Enalaprilat
-Fosinopril
-Ramipril
Contraindication of Angiotensin-Converting-enzyme (ACE) inhibitors
-Presence of allergy
-Impaired renal function
-pregnancy
-Lactation
CAUTION
-Heart failure
-salt volume depletion
-women of childbearing stage
Adverse effect of Angiotensin-Converting-enzyme (ACE) inhibitors
-Fatigue
_Dizziness
-Mood changes
-Headaches
-Anemia
-Ulcers
_rash
-Dermatitis
Selectively bind with the Angiotensin II receptors in vascular smooth muscle and in the adrenal cortex to block Vasoconstriction and release of aldosterone.
Angiotensin II receptor Blockers (ARBs)
Drugs under angiotensin II receptor blockers(ARBS
Family of tan
Losartan
Valsartan
Eprosartan
Olmesartan
Contraindications of angiotensin II receptor blockers
-presence of galactic or renal dysfunction
-Hypovolemia
-Woman of childbearing age
Adverse effect og Angiotensin II receptor blockers(ARBs
Headache
GI complaints including diarrhea
Rash
Dry skin
Alopecia
Inhibits the movement of calcium ions across the membranes of myocardial and arterial muscles cells, altering the action potential and clocking muscle cell contraction.
Calcium-channel blockers
Drugs under Calcium-channel blockers
Family of DIPINE
-Amlodipine
-Felodipome
-Isradipine
-Verapamil
Contraindication for calcium channel blockers
Presence of allgery
Heart block or sick sinus syndrome
Renal or hepatic dysfunction
Pregnancy
Lactation
Adverse effect of Calcium channel blockers
Cans Dizziness, lightheadedness, headache and fatigue
GI Nausea, hepatic injury
CV Hypotension, bradycadia, peripheral edema and heart block
Ingegumentary system Skin flushing, rash
Acts directly on vascular smooth muscle to cause muscle relaxation, leading to vasodilation and drop in BP
Vasodilators
Drugs under Vasodilators
Diazoxide
Hydralazine
Minoxidil
Nitroprusside