Anti-hypertensive drugs Flashcards

1
Q

Acts in the lungs to prevent ACE from converting Angiotensin I to Angiotensin II. Powerful Vasoconstrictor and stimulator of adolsterone release

A

Angiotensin-Converting enzyme (ACE) inhibitors

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2
Q

Drugs under Angiotensin-Converting enzyme (ACE) inhibitors

A

Family name: Pril
-Benazepril
-Captopril
-enalapril
-Enalaprilat
-Fosinopril
-Ramipril

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3
Q

Contraindication of Angiotensin-Converting-enzyme (ACE) inhibitors

A

-Presence of allergy
-Impaired renal function
-pregnancy
-Lactation
CAUTION
-Heart failure
-salt volume depletion
-women of childbearing stage

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4
Q

Adverse effect of Angiotensin-Converting-enzyme (ACE) inhibitors

A

-Fatigue
_Dizziness
-Mood changes
-Headaches
-Anemia
-Ulcers
_rash
-Dermatitis

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5
Q

Selectively bind with the Angiotensin II receptors in vascular smooth muscle and in the adrenal cortex to block Vasoconstriction and release of aldosterone.

A

Angiotensin II receptor Blockers (ARBs)

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6
Q

Drugs under angiotensin II receptor blockers(ARBS

A

Family of tan
Losartan
Valsartan
Eprosartan
Olmesartan

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7
Q

Contraindications of angiotensin II receptor blockers

A

-presence of galactic or renal dysfunction
-Hypovolemia
-Woman of childbearing age

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8
Q

Adverse effect og Angiotensin II receptor blockers(ARBs

A

Headache
GI complaints including diarrhea
Rash
Dry skin
Alopecia

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9
Q

Inhibits the movement of calcium ions across the membranes of myocardial and arterial muscles cells, altering the action potential and clocking muscle cell contraction.

A

Calcium-channel blockers

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10
Q

Drugs under Calcium-channel blockers

A

Family of DIPINE
-Amlodipine
-Felodipome
-Isradipine
-Verapamil

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11
Q

Contraindication for calcium channel blockers

A

Presence of allgery
Heart block or sick sinus syndrome
Renal or hepatic dysfunction
Pregnancy
Lactation

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12
Q

Adverse effect of Calcium channel blockers

A

Cans Dizziness, lightheadedness, headache and fatigue
GI Nausea, hepatic injury
CV Hypotension, bradycadia, peripheral edema and heart block
Ingegumentary system Skin flushing, rash

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13
Q

Acts directly on vascular smooth muscle to cause muscle relaxation, leading to vasodilation and drop in BP

A

Vasodilators

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14
Q

Drugs under Vasodilators

A

Diazoxide
Hydralazine
Minoxidil
Nitroprusside

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