Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm Names > Anti-Hypertensive > Flashcards

Anti-Hypertensive Flashcards

1
Q

Ace Inhibitors

A

Suppresses RAA system and simultaneously inhibits bradykinin degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Ace inhibitors adverse effect

A

Common: photosensitivity, reduced vision, headache, hypotension, conjunctivitis
Distinguishing: cough, taste disturbances
SERIOUS ADVERSE EFFECTS
Hypersensitivity: angioedema*, eyelid edema
Ocular: blur, dry eyes, conjunctival or retinal hemes#, diplopia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

( ACE Inhibitors)

Benazepril

A

Lotensin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Captopril

A

Capoten

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Enalapril

A

Vasotec

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Lisinopril

A

Prinivil

Zestil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Quinapril

A

Accupril

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

(Angiotensin II receptor antagonist ARBs)

Losartan

A

Cozaar

No cough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

(Anti arrhythmic)

Amiodarone

A

Cordarone

> 400mg Whorl Keratopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

( Beta Blockers)

Metoprolol-hydrochlorothiazide

A

Lopressor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Atenolol

A

Tenormin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Metoprolol Succinate

A

Toprol XL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Labetalol

A

Trandate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Propranolol

A

Inderal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

( Calcium Channel Blockers)

Diltiazem Hydrochloride

A

Cordizem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Nifedipine

A

Procardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Verapamil

A

Calan

Isoptin

18
Q

Amlopidine

A

Norvasc

19
Q

( cGMP increaser )

Hydralazine

A

Apresoline

Mechanism of Action
Directly dilates peripheral vessels via hyperpolarization of vascular smooth muscle which thus inhibits Ca++ influx (depolarization)

20
Q

( Antieurythmics )

Digoxin

A

Lanoxin

21
Q

( Alpha 2 Agonist )

Clonidine

A

Catapres

Mechanism of Action
Stimulates central and spinal alpha-2 adrenergic receptors (pre-synaptic and post-junctional)

22
Q

( Diuretic)

Hydrochlorithiazide

A

Microzide
Esidrix

Mechanism of Action
Inhibits reabsorption of NaCl at distal convoluted tubule

23
Q

Hydrochlorodiazide Triamterene

A

Maxzide

Dyazide

24
Q

Chlorothiazide

A

Diuril

25
Q

Furosemide

A

Lasix

Hypokalemia
Nephrotoxic

26
Q

Mannitol

A

Osmitrol

27
Q

Spironolactone

A

Aldactone

Antagonizes aldosterone receptors in distal convoluted tubule resulting in sodium/water loss and potassium retention

28
Q

Triamterene

A

Dyrenium

29
Q

Valsartan

A

Diovan

30
Q

ARBs

Adverse effects / Drug interactions

A

Common: h/a, dizziness
Hypersensitivity: Angioedema, vasculitis

DRUG INTERACTIONS
NSAIDs (antagonism)
Cyclosporine (hyperkalemia)

31
Q

CC-blockers

AE/ DI

A

ADVERSE EFFECTS
Common: headache, dizziness
Ocular: conjunctivitis, diplopia, pain

DRUG INTERACTIONS
Dexamethasone (enhance metabolism)
Cyclosporine, erythromycins, azoles (suppress metabolism)
Ophthalmic Alpha-2 agonists (additive)
Ophthalmic Beta-blockers (additive)
32
Q

Terazosin - alpha -1 receptor blocker

A

Hytrin

33
Q

Beta-Blockers MOA

A

Selective competitive antagonism of β1 receptors reducing systolic BP and CO via negative inotropic and chronotropic effects
Central acting inhibition of sympathetic outflow
Suppression of renin activity

34
Q

Beta-Blockers AE

A

Common: visual disturbances, Decrease tear secretion -> dry eye syndrome, headache
Distinguishing: depression, STM loss
Ocular: increased migrainous scotomata, reduced IOP, glaucoma progression, exacerbation of myasthenia gravis

35
Q

Diuretic MOA

A

Inhibits reabsorption of NaCl at

proximal/distal convoluted tubule & loop of Henle

36
Q

Furosemide AE

A

Common: blurred vision, hypotension, pruritus
Hypersensitivity: Stevens-Johnson syndrome, erythema multiforme
CVS: Decrease K+, vasculitis
Hematology: Anemia

37
Q

Furosemide DI

A

Aminoglycosides (additive nephrotoxicity)
NSAIDs (induced ototoxicity & antagonism)
Carbonic Anhydrase Inhibitors (prolong QT interval)
Erythromycins (prolong QT interval)

Hypersensitivity to sulfonamides

38
Q

Hydrochlorothiazide-AE

A

Common: photosensitivity, headache
Hypersensitivity: Erythema multiforme, Stevens-Johnson syndrome
Hematology: Anemia, leukopenia, thrombocytopenia
Ocular: Angle closure glaucoma

39
Q

Hydrochlorothiazide-DI

A

DRUG INTERACTIONS
CAIs (synergy)
NSAIDs (antagonistic)
Erythromycins (QT prolongation)

40
Q

Spironolactone AE/DI

A

Common: headache
Distinguishing: gynecomastia, menstrual irregularities

IMPORTANT DRUG INTERACTIONS
Cyclosporine (hyperkalemia)
NSAIDs (reduced BP lowering)

41
Q

Clonodine AE/DI

A

ADVERSE EFFECTS
Common: headache, dizziness
Serious: angioedema

42
Q

Hydralazin AE/DI

A

Common: headache, lupus erythematosus

NSAIDs (antagonistic)

Pharm Names (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions