Anti Glaucoma Drugs Flashcards
Miotic agents used in glaucoma
Pilocarpine
Physostigmine
Echothiophate
Carbechol
Doc of choice for the glaucoma closed angle
Pilocarpine
Mechanism of action Miotic agents
Trabecular outflow
Side effects of miotic agents
Ciliary spasm
Induced myopia.
Retinal detachment
Cornea deems
Adverse effects
Anticolinerases must not be given topically
Physostigmine
Echothiophate
If is used cataract will be done
Contraindicated In the lens patients phakic patients
Echothiophate specially causes
Iris cyst
Nasolacrimal duct obstruction
Prostaglandin analogues
Latanoprost
Bimatoprost
Travoprost
Mechanism of latanoprost,bimatoprost,travoprost
Uveoscreal outflow increases
What is the doc of open angle glucoma
Prostaglandin analogues
Only dose one day at night
Adverse effects of prostaglandin analogues
Pcos
Pigmentation of eyelids,eyebrows,peri orbital skin
Cystoid macular edema occurs in dm
Overgrowth of eye lashes tricomegaly
Sand eyes and dry eyes
Prostaglandin analogues are contraindicated in
Uveitis
Herpatic keratitis
As they are inflammatory mediators they cannot be given again inflammatory conditions
What are the sympathomimmetics used. In glaucoma
Epinephrine
Dipivefrine
What are the sympathy mimetic alpha agonist
Apraclonidine
Brimonidine
Recent advances in glaucoma
Netarsudil
Given in open angle glaucoma
Latanoprost + netarsudil
Mechanism of action = trabecular outflow increases
Rhokinase inhibitor
Beta blockers used in the glaucoma
There are two types
Non selective
Selective
Non selective
Timilol
Levobunolol
Metapranolol
Carteolol
Selective
Betaxolol
Mechanism of b blockers in glaucoma
Aqueous production decreases
Used of lanoprost doesn’t work
