Anti FOLATE DRUGS and TB DRUGS

Question 0

Selective inhibitor of bacterial dihydroFOLATE reductase?

Answer 0

TRIMETHOPRIM

Question 1

Competitive inhibitor of dihydropTEROATE synthase?

Answer 1

SULFONAMIDES

Question 2

Used for burns.

Side effect: acute hemolysis in G6PD deficiency, kernicterus and hematotoxicity.

Answer 2

SILVER SULFADIAZINE

Question 3

Interfer with bacterial DNA synthesis by inhibiting TOPOISOMERASE II DNA GYRASE in gram neg organism?

Answer 3

FLUOROQUINOLONES

Question 4

DOC FOR TENDINITIS AND TENDON RUPTURE?

Answer 4

CIPROFLOXACIN

Question 5

Theophylline can cause?

Answer 5

SEIZURE

Question 6

Cardiotoxic florouquinolones?

Answer 6

LEVOFLOXACIN

Question 7

DOC for trichomonas vaginalis?

Answer 7

METRONIDAZOLE

Question 8

Pulmonary infiltrates associated fluroquinolones?

Answer 8

NITROFURANTOIN

Question 9

TB drug can induced lupus?

Answer 9

ISONIAZID

Question 10

Isoniazid can cause neurotoxicity which can be prevented by giving?

Answer 10

PYRIDOXINE (vitamin b6)

Question 11

TB drug which is a potent CYP450 inhibitor?

Answer 11

ISONIAZID

Question 12

A potent CYP450 inducer TB drug?

Answer 12

RIFAMPICIN

Question 13

TB drug cause RED ORANGE URINE?

Answer 13

RIFAMPICIN

Question 14

Inhibit mycolic acid synthesis tb drug?

Answer 14

ISONIAZID

Question 15

TB DRUG inhibit DNA dependent RNA polymerase

Answer 15

RIFAMPICIN

Question 16

TB drug cause colorblindness?

Answer 16

ETHAMBUTOL

Question 17

Most hepatotoxic TB drug and cause HYPERURICEMIA?

Answer 17

PYRAZINAMIDE

Question 18

Most active drug against m. Leprae?

Answer 18

DAPSONE