Anti-emetics Flashcards

1
Q

Cyclizine

A

H1 receptor antagonist.
50mg/8h PO/IV/IM.
For GI causes.

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2
Q

Cinnarizine

A

H1 receptor antagonist.
30mg/8h PO.
For vestibular disorders.

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3
Q

Metoclopramide

A

D2 receptor antagonist.
10mg/8h PO/IV/IM.
For GI causes.
Pro-kinetic.

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4
Q

Domperidone

A

D2 receptor antagonist.
60mg/12h PR, 20mg/6h PO.
Pro-kinetic.

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5
Q

Prochlorperazine

A

D2 receptor antagonist.
12.5mg IM, 5mg/8h PO.
For vestibular/GI causes.

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6
Q

Haloperidol

A

D2 receptor antagonist.
1.5mg/12h PO.
For chemical causes, e.g. opioids.

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7
Q

Ondansetron

A

5HT3 receptor antagonist.

4-8mg/8h IV slowly, doses can be higher for e.g. emetogenic chemotherapy.

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8
Q

Hyoscine hydrobromide

A

200-600mcg SC/IM.

Antimuscarinic, therefore also antispasmodic and antisecretory (don’t prescribe with pro-kinetic).

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9
Q

Dexamethasone

A

6-10mg/d PO/SC.
Unknown mode of action.
Adjuvant.

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10
Q

Midazolam

A

2-4mg/d SC (syringe driver)
Unknown action.
Anti-emetic effect outlasts sedative effect.

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