Anti-coagulants Flashcards

1
Q

Vit K antagonist

A

Warfarin

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2
Q

Vit- K ANTAGONIST inhibits the synthesis of which Vit- K factors?

A

II, VII, IX, and X

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3
Q

Potentiator of Antithrombin Heparins

A

Unfractionated Heparin

Low molecular weight Heparins = Enoxaparin Dalteparin

Synthetic Heparinoids = Fondaparinux

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4
Q

Direct Thrombin Inhibitors

A

Hirudin family: Lepirudin, Bivalirudin, Argatroban, Dabigatran

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5
Q

Active Factor Xa Inhibitors

A

Apixaban, Rivaroxaban

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6
Q

Antidote to Heparin

A

Protamine sulfate

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7
Q

Antidote to Warfarin

A

Vit K1 (Phytonadione)

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8
Q

Fibrinolytics (Thrombolytics)

A
  1. Tissue plasminogen activator (tPA drugs) = Alteplase, Reteplase, Tenecteplase
  2. Streptokinase
  3. Anistreplase
  4. Urokinase
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9
Q

Treatment of Bleeding :
Antidote to fibrinolytics

A

Aminocaproic acid

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10
Q

Treatment of heavy menstrual bleeding: Antifibrinolytic drug?

A

Tranexamic acid

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