Anti-cholesterol agents Flashcards
HMG-COA reductase inhibitor
Lowers LDL
Statins
hepatotoxicity
rhabdomyolysis
myopathy
Statins
Bile acid binding resin
Lowers LDL
Cholestyramine
SE:
constipation
steatorrhea
cholestyramine
Reduces ALL building blocks for hyperlipidemia,
Increases HDL
Lowers LDL and TG
Niacin
SE: flushing, hyperglycemia, hyperurecemia
Niacin
Cholesterol absorption blocker, lowers LDL
Ezteimibe
Hepotoxicity, esp with STATIN use
Eztetimibe
PPAR-a activator Upregulates lipoprotein lipase
Lowers TG
fibrates
SE: gallstones, additive myopathy
Fibrates
Why are statins used in the mgt of CAD?
For stabilization of atherosclerotic plaques
What are the drugs that cause flushing?
Vancomycin
Adenosine
Niacin
CCB