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CPR - drugs > Anti-arrhythmic > Flashcards

Anti-arrhythmic Flashcards

1
Q

Digoxin

A

MOA: Inhibits Na+/K+ ATPase –> increased intracellular Ca2+ –> increased contractility.

Clinical uses: CHF, atrial tachycardias

Toxicity: Arrhythmias, visual disturbances

Carefully monitor w/ anti-coagulatns

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2
Q

Procainamide

A

Anti arrhythmic class IA

MOA: Inhibit Na+ Channels

Treats: Atrial and ventricular tachycardias

Toxicity: Arrhythmias, hypersensitivity reactions - drug induced SLE

DDIs (drug-drug interaction) with proton pump inhibitors (omeprazole and esomeprazole).

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3
Q

Lidocaine

A

Anti arrhythmic class IB

MOA: Inhibit Na+ Channels

Treats: ventricular tachycardias

Toxicity: CNS

DDIs: NSAIDs, acetazolamide, corticosteroids, spironolactone

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4
Q

Flecainide

A

Anti arrhythmic class IC

MOA: Inhibit Na+ Channels

Treats: atrial tachycardias in patients w/ normal ventricular function

Toxicity: Arrhythmias

DDIs: Isolated from streptococci

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5
Q

Metoprolol

A

Anti-arrhythmic class II

MOA: Beta-1 antagonist (propanolol is non-selective beta-antagonist)

Treats: Atrial and ventricular tachycardia

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6
Q

Amiodarone

A

Anti arrhythmic Class III

MOA: Inhibit K+ and Na+ channels

Treats: Atrial and ventricular tachycardias

Toxicity: long QT, hypotension, pulmonary fibrosis, tissue deposits, drug interactions

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7
Q

Anti arrhythmic Class III

A

Amiodorone

Dronaderone

Dofetilide

Sotalol

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8
Q

Dronaderone

A

Anti arrhythmic Class III

MOA: Inhibit K+ and Na+ channels

Treats: Atrial and ventricular arrhythmias

Toxicity: long QT, depressed conduction

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9
Q

Dofetilide

A

Anti arrhythmic Class III

MOA: Inhibit K+ channels

Treats: Atrial arrhythmias

Toxicity: long QT

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10
Q

Sotalol

A

Anti arrhythmic Class III

MOA: Inhibit K+ channels and beta-adrenergic receptors

Treats: Atrial and ventricular arrhythmias

Toxicity: long QT

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11
Q

Verapamil

A

Anti arrhythmic Class IV

MOA: Voltage gated Ca2+ channel inhibitor, cardiac preferring

Treats: Atrial arrhythmias>angina, hypertension

Toxicity: hypotension, tachycardia

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12
Q

Nifedipine

A

L-type Ca2+ channel blocker (amlodipine etc..)

MOA: Voltage gated Ca2+ channel inhibitor, VSM preferring

Treats: angina, hypertension

Toxicity: hypotension, tachycardia

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13
Q

Adenosine

A

Nucleotide receptor agonist

MOA: Activates adenosine receptors

Treats: Conversion of atrial arrhythmias

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CPR - drugs (6 decks)

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