Anti Anxiety Flashcards
1
Q
What class of drug used for anti anxiety
A
Benzodiazepine
2
Q
What can benzodiazepine be used for
A
Anxiolytic Treat insomnia Muscle relaxant Premedication for sedation as part of balanced anaesthesia Alcohol withdrawal
3
Q
Mechanism of action of benzodiazepine
A
Bind to bzd binding site on gaba receptor on chloride ion channel, increase frequency of channel opening, promoting action GABA
4
Q
Name the various benzodiazepines
A
Midazolam 2-3h
Lorazepam, alprazolam 8h
Diazepam 1 day
5
Q
Adverse effects of benzodiazepine
A
Dose related drowsiness
Diminished motor skills, increased reaction time
Anterograde amnesia
Hypomanic, garrulousness
Can cross placenta barrier and cause floppy child syndrome
Tolerance/dependence/withdrawal if administered frequently
6
Q
How is benzodiazepine administered
A
Oral or parenteral