Anti-allergy Flashcards

1
Q

Flonase

A

Fluticasone Propionate

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2
Q

Atarax

A

Hydroxyzine Hydrochloride

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3
Q

Nasonex

A

Mometasone Furoate Monohydrate

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4
Q

Astelin

A

Azelastine Hydrochloride

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5
Q

Xyzal

A

Levocetirizine Dihydrochloride

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6
Q

Dosage form for Astelin

A

(0. 1%) Each spray delivers 137 mcg drug. ~100 sprays/bottle. Prime with 4 sprays.
* Greatest amount of drug delivered in one spray
* LEAST amount of sprays per bottle.

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7
Q

Dosage form for Nasonex

A

Each spray delivers 50 mcg drug. ~120 sprays/bottle. Before first use, 10 actuations! (Almost identical to Flonase, but you NEED to prime this one more)

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8
Q

Dosage form for Atarax

A

Tablets: 10, 25, 50 mg
Syrup: 10mg/5mL
Injection: 25, 50 mg/mL
Highest dosage for anti-allergy

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9
Q

Dosage form for Flonase

A

Each spray deliver 50 mcg drug. ~120 sprays/amber bottle. (Almost identical to Nasonex, but you don’t need to prime 10 times!)

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10
Q

Dosage form for Xyzal

A

Tablets: 5 mg
Oral Solution: 2.5 mg/5mL
Smallest dosage for anti-allergy

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11
Q

Dosage of Xyzal for Adults and Children (>12)?

A

5mg (or 2 tsp) QPM

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12
Q

Dosage of Xyzal for Children 6-11?

A

2.5 QPM

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13
Q

Dosage of Flonase for people 4+ yo?

A

RECOMMENDED and MAX: 2 sprays in each nostril QD (200 mcg)

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14
Q

Good dose for maintenance on Flonase?

A

Reduce it down to 100 mcg/day (1 spray each nostril QD)

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15
Q

Most adolescents should be started on what dose of Flonase?

A

100 mcg/day (1 spray each nostril QD)

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16
Q

Dosage of Atarax for allergies?

A

25mg TID or QID (75-100 mg)

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17
Q

Children >6 yo on Atarax?

A

50-100 mg QD divided doses

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18
Q

Children <6 yo on Atarax?

A

50mg QD divided doses

19
Q

Dosage of Nasonex in people 2+ yo?

A

2 sprays in each nostril QD, starting 2-4 weeks prior to the anticipated start of the pollen season.

20
Q

Difference between Flonase and Nasonex dosage?

A

Nasonex can be given as young as 2 yo; Flonase is only 4 yo.

21
Q

Dosage of Astelin for people 12+ yo?

A

2 sprays in each nostril BID!

22
Q

What are the age specific requirements for each drug?

A
Nasonex= 2+
Flonase= 4+
Atarax=Under 6
Xyzal= 6+
Astelin= 12+
23
Q

MOA: Astelin

A

H1-receptor antagonist that blocks histamine release in peripheral tissues

24
Q

MOA: Xyzal

A

H1-receptor competitive agonist that blocks histamine from affecting receptors in the peripheral tissues

25
Q

MOA: Atarax

A

H1-receptor antagonist in peripherals. May also suppress histamine in CNS.

26
Q

MOA: Flonase

A

Glucocorticoid receptor agonist. It reduces the accumulation of surface basophilic cells resulting in a localized anti-inflammatory effect.

27
Q

MOA: Nasonex

A

Adrenocorticoid receptor agonist. It reduces the synthesis of specific enzymes so the drug carries out an anti-allergy and anti-inflammatory action.

28
Q

Which drugs have very minimal systemic activity?

A

Flonase and Nasonex

29
Q

Which drug cards specifically mention the higher systemic bioavailability of these drugs?

A

Astelin (40% bioavailability) and Xyzal (91% albumin bound)

30
Q

What two meds have it specifically mention that it either reaches blood or reaches site of action within an hour?

A

Atarax and Xyzal

31
Q

Which drug has the longer half-life: Astelin or Xyzal?

A

Astelin (22 hrs) vs. Xyzal (8-9 hrs)

32
Q

Which two drugs might interact with systemic corticosteroids?

A

Nasonex and Flonase

33
Q

Which two drug cards specifically mention CNS depressants as DDI that might cause CNS depression?

A

Atarax and Astelin

34
Q

Which drug card specifically mentions another drug that may increase its plasma level?

A

Xyzal

35
Q

Which anti-allergy has no pregnancy category established?

A

Atarax

36
Q

Which anti-allergy has the best outcome for pregnancy?

A

Xyzal

37
Q

Which two drugs have 2 specific populations its contraindicated in?

A

Xyzal=Patients under 11 with severe renal disease

Atarax=Early pregnancy

38
Q

What drug is the only one that doesn’t mention “use with caution in lactating women”?

A

Astelin

39
Q

Which two specifically DON’T mention drowsiness or fatigue as a side effect?

A

Flonase and Nasonex

40
Q

Which two specifically mention use with caution in those with infections?

A

Flonase and Nasonex

41
Q

Which one is a patient most likely to complain about a bitter taste?

A

Astelin

42
Q

Which two specifically ask you to avoid alcohol while on it?

A

Atarax and Xyzal

43
Q

Which med requires to ask specifically for medical conditions (i.e. asthma, glaucoma, BPH, heart disease, diabetes, thyroid disease)

A

Xyzal