Anti-allergy

Question 1

Flonase

Answer 1

Fluticasone Propionate

Question 2

Atarax

Answer 2

Hydroxyzine Hydrochloride

Question 3

Nasonex

Answer 3

Mometasone Furoate Monohydrate

Question 4

Astelin

Answer 4

Azelastine Hydrochloride

Question 5

Xyzal

Answer 5

Levocetirizine Dihydrochloride

Question 6

Dosage form for Astelin

Answer 6

(0. 1%) Each spray delivers 137 mcg drug. ~100 sprays/bottle. Prime with 4 sprays.
* Greatest amount of drug delivered in one spray
* LEAST amount of sprays per bottle.

Question 7

Dosage form for Nasonex

Answer 7

Each spray delivers 50 mcg drug. ~120 sprays/bottle. Before first use, 10 actuations! (Almost identical to Flonase, but you NEED to prime this one more)

Question 8

Dosage form for Atarax

Answer 8

Tablets: 10, 25, 50 mg
Syrup: 10mg/5mL
Injection: 25, 50 mg/mL
Highest dosage for anti-allergy

Question 9

Dosage form for Flonase

Answer 9

Each spray deliver 50 mcg drug. ~120 sprays/amber bottle. (Almost identical to Nasonex, but you don’t need to prime 10 times!)

Question 10

Dosage form for Xyzal

Answer 10

Tablets: 5 mg
Oral Solution: 2.5 mg/5mL
Smallest dosage for anti-allergy

Question 11

Dosage of Xyzal for Adults and Children (>12)?

Answer 11

5mg (or 2 tsp) QPM

Question 12

Dosage of Xyzal for Children 6-11?

Answer 12

2.5 QPM

Question 13

Dosage of Flonase for people 4+ yo?

Answer 13

RECOMMENDED and MAX: 2 sprays in each nostril QD (200 mcg)

Question 14

Good dose for maintenance on Flonase?

Answer 14

Reduce it down to 100 mcg/day (1 spray each nostril QD)

Question 15

Most adolescents should be started on what dose of Flonase?

Answer 15

100 mcg/day (1 spray each nostril QD)

Question 16

Dosage of Atarax for allergies?

Answer 16

25mg TID or QID (75-100 mg)

Question 17

Children >6 yo on Atarax?

Answer 17

50-100 mg QD divided doses

Question 18

Children <6 yo on Atarax?

Answer 18

50mg QD divided doses

Question 19

Dosage of Nasonex in people 2+ yo?

Answer 19

2 sprays in each nostril QD, starting 2-4 weeks prior to the anticipated start of the pollen season.

Question 20

Difference between Flonase and Nasonex dosage?

Answer 20

Nasonex can be given as young as 2 yo; Flonase is only 4 yo.

Question 21

Dosage of Astelin for people 12+ yo?

Answer 21

2 sprays in each nostril BID!

Question 22

What are the age specific requirements for each drug?

Answer 22

Nasonex= 2+
Flonase= 4+
Atarax=Under 6
Xyzal= 6+
Astelin= 12+

Question 23

MOA: Astelin

Answer 23

H1-receptor antagonist that blocks histamine release in peripheral tissues

Question 24

MOA: Xyzal

Answer 24

H1-receptor competitive agonist that blocks histamine from affecting receptors in the peripheral tissues

Question 25

MOA: Atarax

Answer 25

H1-receptor antagonist in peripherals. May also suppress histamine in CNS.

Question 26

MOA: Flonase

Answer 26

Glucocorticoid receptor agonist. It reduces the accumulation of surface basophilic cells resulting in a localized anti-inflammatory effect.

Question 27

MOA: Nasonex

Answer 27

Adrenocorticoid receptor agonist. It reduces the synthesis of specific enzymes so the drug carries out an anti-allergy and anti-inflammatory action.

Question 28

Which drugs have very minimal systemic activity?

Answer 28

Flonase and Nasonex

Question 29

Which drug cards specifically mention the higher systemic bioavailability of these drugs?

Answer 29

Astelin (40% bioavailability) and Xyzal (91% albumin bound)

Question 30

What two meds have it specifically mention that it either reaches blood or reaches site of action within an hour?

Answer 30

Atarax and Xyzal

Question 31

Which drug has the longer half-life: Astelin or Xyzal?

Answer 31

Astelin (22 hrs) vs. Xyzal (8-9 hrs)

Question 32

Which two drugs might interact with systemic corticosteroids?

Answer 32

Nasonex and Flonase

Question 33

Which two drug cards specifically mention CNS depressants as DDI that might cause CNS depression?

Answer 33

Atarax and Astelin

Question 34

Which drug card specifically mentions another drug that may increase its plasma level?

Answer 34

Xyzal

Question 35

Which anti-allergy has no pregnancy category established?

Answer 35

Atarax

Question 36

Which anti-allergy has the best outcome for pregnancy?

Answer 36

Xyzal

Question 37

Which two drugs have 2 specific populations its contraindicated in?

Answer 37

Xyzal=Patients under 11 with severe renal disease | Atarax=Early pregnancy

Question 38

What drug is the only one that doesn't mention "use with caution in lactating women"?

Answer 38

Astelin

Question 39

Which two specifically DON'T mention drowsiness or fatigue as a side effect?

Answer 39

Flonase and Nasonex

Question 40

Which two specifically mention use with caution in those with infections?

Answer 40

Flonase and Nasonex

Question 41

Which one is a patient most likely to complain about a bitter taste?

Answer 41

Astelin

Question 42

Which two specifically ask you to avoid alcohol while on it?

Answer 42

Atarax and Xyzal

Question 43

Which med requires to ask specifically for medical conditions (i.e. asthma, glaucoma, BPH, heart disease, diabetes, thyroid disease)

Answer 43

Xyzal