Anterior Pituitary

Question 1

MC pituitary tumor

Answer 1

Prolactinoma

Question 2

MC pituitary tumor but clinically insignificant

Answer 2

Alpha subunit of FSH secreting tumors(no manifestation, mostly diagnosed postpartum)

Question 3

Types of prolactinoma

Answer 3

Miroadenoma
Macroadenoma
Giant prolactinoma

Question 4

Microadenoma

Answer 4

Less than 1 cm; 90% of prolactinoma F:M- 20:1

Question 5

MC prolactinoma

Answer 5

Microadenoma

Question 6

Macroadenoma

Answer 6

1-4cm; 9% of prolactinomas; F:M- 1:1

Question 7

Giant prolactinoma

Answer 7

> 4 cm ; 1% of prolactinomas; F:M-1:1

Question 8

Age group of prolactinoma

Answer 8

25-45 yrs old

Question 9

Prolactinoma or ommon in men or women

Answer 9

Women

Question 10

Cause of prolactinoma if <20 yrs old

Answer 10

Genetic syndrome

Question 11

Genetic syndromes causing prolactinomas

Answer 11

MEN-1 syndrome
McCune albright syndrome
Carney’s complex

Question 12

Tumor generally present with what effect

Answer 12

Hormonal effect; since commonly tumors are microadenomas

Question 13

Clinical presentation of prolactinoma in 25-45 yrs old female

Answer 13

Galactorrhea-amenorrhea complex(clinically sec amenorrhea)

Infertility

Question 14

Infertilty in prolactinoma is due to

Answer 14

Prolactin suppresses HPG axis and produces luteal phase dysfuntion

Question 15

Clinical presentation of prolactinoma in male

Answer 15

Loss of libido

Erectile dysfuntion

Question 16

Other common clinical presentation of prolactinoma

Answer 16

Osteoporosis of spine

Insulin resistance

Question 17

Screenin test of choice for prolactinoma

Answer 17

Fasting prolactin levels