Anterior Ischaemic Optic Neuropathy Flashcards
What is anterior ischaemic optic neuropathy?
A medical condition involving loss of vision caused by damage to the optic nerve as a result of insufficient blood supply
What are the two general types of anterior ischaemic optic neuropathy?
- Arteritic AION
- Non-arteritic AION
What is arteritic anterior ischaemic optic neuropathy?
Loss of vision as a result of temporal arteritis
What causes non-arteritic anterior ischaemic optic neuropathy?
Due to non-inflammatory disease of small blood vessels
What do these cards mostly relate to?
Non-arteritic anterior ischaemic optic neuropathy
Where are the cards on arteritic anterior ischaemic optic neuropathy?
In temporal arteritis
What is non-arteritic anterior ischaemic optic neuropathy?
An isolated white-matter stroke of the optic nerve
What are the risk factors for non-arteritic anterior ischaemic optic neuropathy?
- Predisposition due to type of optic disc
- Cardiovascular risks
- Nocturnal arterial hypotension
What type of optic disc predisposes to non-arteritic anterior ischaemic optic neuropathy?
‘Crowded’ optic disc
What is the optic disc?
The place where the axons from the retinal ganglion cells collect into the optic nerve
What must optic nerve penetrate?
The wall of the eye
How large is the hole in the eye for optic nerve?
Usually 20-30% larger than the nerve diameter
What is a crowded optic disc?
Where the optic nerve is nearly as large as the opening in the back of the eye
What are the cardiovascular risk factors for non-arteritic anterior ischaemic optic neuropathy?
- Diabetes
- Hypertension
- High cholesterol levels
What is nocturnal arterial hypotension?
When there is a marked fall in BP when falling asleep
When does non-arteritic anterior ischaemic optic neuropathy typically present?
Suddenly upon waking
What are the features of non-arteritic anterior ischaemic optic neuropathy?
- Seeing poorly in one eye
- No pain
How is vision affected in non-arteritic anterior ischaemic optic neuropathy?
- Vision in affected eye is obscured by a dark shadow
- Often just the upper or lower half of vision
- Usually closer to the nose
What happens to 40% of people with non-arteritic anterior ischaemic optic neuropathy after 6 months?
Their vision will have improved by 3 lines of a Snellen chart
What will have happened to 10% of people with non-arteritic anterior ischaemic optic neuropathy after 6 months?
Their vision will have worsened by 3 lines of a Snellen chart
What % of patients with non-arteritic anterior ischaemic optic neuropathy have opposite eye involvement within 5 years?
15-20%
Is involvement of the opposite eye in non-arteritic anterior ischaemic optic neuropathy devastating?
Not always as impairment can be mild-moderate
What do patients with non-arteritic anterior ischaemic optic neuropathy often have on examination?
Some or all signs of optic neuropathy
What are some signs of optic neuropathy?
- Decreased visual acuity
- Dyschromatopsia
- RAPD
- Swollen optic nerve with splinter haemorrhages
- Visual field defect
What is dyschromatopsia?
Loss of colour vision
Which sign of optic neuropathy is very sensitive for optic nerve dysfunction?
Dyschromatopsia
How is non-arteritic anterior ischaemic optic neuropathy diagnosed?
Clinically
What are the main differentials for non-arteritic anterior ischaemic optic neuropathy?
- Arteritic anterior ischaemic optic neuropathy
- Optic neuritis
When should A-AION be suspected instead of NA-AION?
In all patients over the age of 50
How should patients with NA-AION over 50 be evaluated?
Evaluate to exclude A-AION
What are the symptoms of A-AION?
- Painful jaw muscle spasms
- Scalp tenderness
- Unintentional weight loss
- Fatigue
- Myalgia
- Loss of appetite
What can optic neuritis be secondary to?
MS
How can non-arteritic anterior ischaemic optic neuropathy be treated?
There is no accepted way of reversing the condition
How can non-arteritic anterior ischaemic optic neuropathy be prevented?
Risk factor modification
What may be helpful in reducing effects of non-arteritic anterior ischaemic optic neuropathy in the early stages?
High dose corticosteroids