Antepartum Flashcards

1
Q

At risk –> prenatal testing

7

A

Maternal age > 35 years
Birth of previous infant with chromosomal abnormalities or neural tube defect
Chromosomal abnormality in family member
Gender if mom is carrier of X-linked disorder
Pregnancy after 3 or more spontaneous abortions
Maternal Rh sensitization
Elevated levels of maternal serum AFP

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2
Q

Genetic Counseling

A

Availability
Facilities with maternal-fetal medicine services
State agencies
Agencies focus on a specific birth defect
(i.e., March of Dimes)

Process of genetic counseling
Diagnosis may never be established

Supplemental services

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3
Q

Environmental Influences

Causative agents - 6

A

Teratogens
Agents that cause birth defects
Multifactorial

Causative agents
Maternal infectious agents
Drugs, Rubella & Vaccine
Pollutants
Ionizing radiation
Maternal hyperthermia
Maternal co-morbidities
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4
Q

Multifactorial Disorders

A

An interaction of genetic tendency and environmental factors.
Affected close relatives
Gender
Geography

Cardiac anomalies
Cleft lip and palate
Neural tube defects

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5
Q

Prevention and Treatment for genetic, multifactorial conditions

A

Ideally before conception
Appropriate medical therapy for diseases
Identification of risks
Preventive treatment tailored to identified risks
400 mcg of folic acid daily before conception

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6
Q

Evaluation of the Fetus

Diagnostic (3) and Assessment (2)

A
Diagnostic Testing
Ultrasound
Amniocentesis
CVS
PUBS

Assessment of Fetal Well-Being
Nonstress Test
Biophysical Profile

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7
Q

Amniocentesis

A

Invasive test to identify chromosomal or biochemical abnormalities
Between 15 and 20 weeks
Risk of spontaneous abortion infection, ruptured membranes

In 3rd trimester to assess:
Fetal lung maturity
Detects fetal hydrops; erythroblastosis fetalis

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8
Q

PUBS – Percutaneous umbilical blood sampling

A

PUBS Invasive
after 16 wks
Blood gas, CBC, coag, Rh
Results in hrs

Cord laceration, thromboemboli, infection, spontaneous ab, PROM

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9
Q

Chronic villus sampling

A

CVS Invasive
10-13 wks
Karyotyping to identify chromosomal abnormalities
Results in 48 hrs
0.5% to 2.0% chance of spontaneous abortion & limb abnormalities

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10
Q

Non Stress Test
Accelerations indicate…
Reactive NST…

A

Assess fetal well-being – uteroplacental function
Noninvasive
After 28 wks

Accelerations in FHR indicative of
Adequate O2 of CNS
Healthy neural pathway from fetal CNS to FH
Ability of FH to respond to stimuli

Reactive NST
At least 2 FHR acceleration within 20 minute period
At least 15 beats above baseline
Lasting at least 15 seconds

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11
Q

Biophysical Profile (BPP)

A
Ultrasound evaluation of 5 parameters in fetus
Breathing movement
Movement of limbs or body
Tone – extension/flexion of extremities
Amniotic fluid index (AFI)
Reactive FHR with activity  (NST)

2 points for each
(8 to 10 normal, 4 to 6 possible compromise 0 to 2 high perinatal mortality)
Usually in 3rd trimester but may be done after 24 wks

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12
Q

Indications for BPP (10)

A
Maternal diabetes mellitus
Maternal heart disease
Maternal chronic hypertension
Maternal sickle cell anemia
Maternal renal disease
Hx previous stillbirths
Rh sensitization
Maternal preeclampsia or eclampsia
Suspected post maturity
Intrauterine growth restriction
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13
Q

Maternal Co-Morbidities

A

Acute and chronic illnesses present before pregnancy, develop during pregnancy affect fetal health and outcome

Assess for symptoms  
Neurologic
Respiratory
Cardiovascular
GI
GU
Musculo-skeletal
Integumentary
Psychosocial
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14
Q
Maternal co-morbidities can affect fetal health and outcome
Respiratory
CV
Hemoglobinopathies
Endocrine
Autoimmune disorders
Developmental disabilities
A

Respiratory
Asthma; Cystic Fibrosis

Cardiovascular Anomalies or Disease
Anomalies;

Hemoglobinopathies
Sickle cell disease; Thalassemia

Endocrine
Diabetes; Thyroid Conditions

Autoimmune Disorders
Multiple Sclerosis, Systemic Lupus, Erythematosis

Developmental Disabilities
Physical Disabilities
Cancer

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15
Q

Psychosocial Distress (9)

A
Increasing Anxiety
Inability to establish communication
Inappropriate responses or actions
Denial of pregnancy
Inability to cope with stress
Intense preoccupation with the sex of the baby
Failure to acknowledge quickening
Failure to plan and prepare for the baby (e.g. living arrangements, clothing, feeding supplies
Indications of substance abuse
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16
Q

Behavioral Health Disorders – Nursing Interventions

A

Provide strategies to…

Help decrease anxiety
Keep her oriented to reality
Promote optimal functioning during pregnancy and while in labor.

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17
Q

Smoking during pregnancy has serious health risks including…
8
Alcohol and other drugs easily pass from mother to baby through placenta

A
Bleeding complications 
Miscarriage 
Stillbirth 
Prematurity
Placenta previa
Placental abruption
Low birth weight (LBW)
Sudden infant death syndrome
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18
Q

Substance Abuse

Legal Considerations

A

Legal considerations

Some women who abuse substances may face criminal charges
Nurses who encourage prenatal care, counseling, and treatment are of greater benefit to mother and child than prosecution

The role of the nurse is to support the patient in her efforts to achieve a healthy outcome of her pregnancy

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19
Q

Perinatal Infections

STIs TORCH

A

STIs
Chlamydia, Gonorrhea, Syphilis, HPV, HIV + AIDS

TORCH
Toxoplasmosis
Other: Varicella, Hepatitis B
Rubella
Cytomegalovirus
Herpes Simplex
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20
Q

How perinatal infections affect the fetus
Nursing Dx? (4)
Outcome?
Interventions?

A
Nursing Diagnoses?
Ineffective Health Maintenance
Grieving
Readiness for Enhanced Knowledge
Ineffective Coping

Outcome?
Interventions?

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21
Q

Diabetes Mellitus

Classifications

A

Classification
Pregestational - Diabetes Mellitus existing before pregnancy
Type 1 diabetes
Type 2 diabetes

Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or recognition during pregnancy (2nd or 3rd trim)

Prediabetes: impaired fasting glucose (IFG)

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22
Q

Pregnancy and Insulin Production

Steps to increased blood glucose

A

Placenta produces hormones (estrogen, cortisol and human placental lactogen

These hormones inhibit the functioning of insulin

Blood glucose is increased

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23
Q

Changing Insulin Needs during pregnancy

A

First trimester: Insulin need is reduced
Second trimester: Insulin need increases
Third trimester: Insulin requirement gradually increase to 36 weeks

Delivery: Maternal insulin requirement drops drastically to pre-pregnancy level - intervention: frequent BS during labor

Breastfeeding mother maintains lower insulin requirement

Weaning breastfeeding mother returns to prepregnancy level

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24
Q

ADA Guidelines: Preconception Care

A

Maintain A1C levels

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25
Q

Gestational Diabetes and Pregnancy

Screening

A

Glucose/Carbohydrate intolerance with onset during pregnancy
7% of all pregnancies – as high as 15% in some populations
Screening: patient history, or clinical risk factors, or glucose challenge test

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26
Q

Symptoms warranting OGTT (6)

A
Persistent glycosuria on 2 visits
 Proteinuria
 Urinary frequency after 1˚ trimester
 Excessive thirst or hunger
Recurrent monilial infections
Polyhydramnios, suspected large fetal size, or  increased fundal height for date
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27
Q

Low Risk for gestational Diabetes (4)

High risk for gestational diabetes (4)

A
Low Risk
Normal weight before pregnancy
Under age 25
No hx unexplained stillbirth
No diabetes in immediate family
High Risk
Ethnicity: Af Am, Hisp, Native Am
HTN
Hypercholesterolemia
GD or LGA in previous pregnancy
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28
Q

Tx for prenatal clinical development for different types of DM

A

Treatment for Mom
Diet

If not managed well on diet, add meds
Drugs
Type 1
Insulin - may be admitted during 2nd trimester to regulate

Type 2 and GDM
Oral hypoglycemic (Glyburide & Metformin) may be effective; Prescribed, though not approved by FDA (Category B / C)
Insulin, if diet and oral hypoglycemics not effective

Treatment for Baby - After delivery

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29
Q

Danger signs – First Trimester (6)

A

Vaginal bleeding, Abdominal pain
Severe, persistent vomiting
Indicators of infection, hypoxia

Ectopic
Hydatiform mole
Spontaneous abortion
Hyperemesis gravidarum
Perinatal infections
Hypoxia (maternal chronic or acute)
30
Q

Hydatiform Molar Pregnancy

Symptoms and risks

A

Gestational Trophoblastic Disease
Proliferation and degeneration of trophoblastic villi

Symptoms
Vaginal bleeding, size/date discrepancy
excessive nausea/vomiting, abdominal pain

Risks – choriocarcinoma – repeat mole
Tx: remove uterine contents (D+C)

31
Q

Ectopic Pregnancy
Symptoms
Treatment in Fallopian tubes

A
Symptoms
Missed period
Positive pregnancy test (though low hCG)
Abdominal pain
Vaginal spotting

Treatment in Fallopian Tubes
Medical
If tube not ruptured, Methotrexate IM to dissolve embryo
Surgical
If tube not ruptured, laparoscopic salpingostomy to remove products of conception and salvage the tube
If tube is ruptured, laparoscopic salpingectomy
Counseling

32
Q

Spontaneous Abortion

A

Before 20 weeks of gestation
bleeding, cramping, abdominal pain, decreased symptoms of pregnancy

D+C if necessary
Emotional support

33
Q

Incompetent Cervix aka Cervical Insufficiency

A
Painless dilation and cervical effacement
Before second trimester
Bedrest
Cerclage
McDonald
Shirodkar
34
Q

Severe Morning Sickness
Hyperemesis Gravidarum
Symptoms (5)

A

Excessive vomiting
Unable to retain fluids

Dehydration
Electrolyte imbalance
Acid-Base imbalance
Starvation Ketosis
Weight Loss
35
Q

Severe morning sickness

Dx and Interventions

A
1. NPO + IVF
    Emotional Support
2. Slowly add food
    Monitor weight
    Continue support
36
Q

Danger signs – 2nd trimester

9

A

Vaginal bleeding, Abdominal pain; Leaking amniotic fluid; Fundal height; Glycosuria; HTN/Proteinuria; Absence of fetal movement

Spontaneous abortion
Hyperemesis Gravidarum
Perinatal infections
Hypoxia

Fetal compromise
PROM
Preterm Labor
Preeclampsia
HELLP Syndrome
37
Q

rH incompatibility

A

Rh- mom plus Rh+ dad
AKA
Rh Isoimmunization = antibodies (which can cross the placenta destroy the baby’s RBCs resulting in massive hemolysis

RhoGAM 28 -34 wks (prenatal dose)
RhoGAM 24 to 72 hours post partum if baby is Rh+

38
Q

Coombs Test
Indirect vs. Direct

Negative vs. Positive

A

Indirect = antibody screen – measures number of Rh+ antibodies in mother’s blood

Direct = detects antibodies coated Rh+ cells in infant’s blood
Done after delivery

Negative indirect coombs
Mother given RhoGAM

Positive indirect coombs “sensitized”
Fetus monitored for hemolytic disease of the newborn (erythroblastosis fetalis)

39
Q

ABO incompatibility

A

Mother type O
Previous exposure to a protein (antigen)
Anti-antigen antibodies present in mom

Fetus A, B, or AB
A, B, AB all contain the protein antigen not present in O

Hemolysis of fetal RBCs

40
Q

PROM

Premature rupture of membranes

A

Cause: Multifactorial
The earlier the gestation, the more likely infection and inflammation may be causative factors

Symptom: gush / trickle / leaking of fluid from vagina
Confirmation of amniotic fluid??
Nitrazine or ferning

41
Q

PROM

Criteria influencing the treatment plan:

A

Establish gestational age
Ultrasound to assess fetus

In labor? Sxs of Infection?
If advanced labor or infection, deliver fetus if viable

-> induction or c/s depending upon gestational age, distress

42
Q

Assessment: Twins

Ultrasound findings

A

Ultrasound:
closed cervix
normal growth for both fetus A & fetus B
excessive amniotic fluid (polyhydramnios)

43
Q

Discordant twins

Twin to Twin transfusion

A

Identical twins born at 28 weeks

Drastic Different weights

44
Q

Multiple Gestation

Nursing Dx

A

Risk of Preterm Labor

Risk of Premature Rupture of Membranes

45
Q

Warning signs of preterm labor (7)

A
Abdominal pain
Contractions
Pelvic Pressure
Vaginal Discharge that is heavy
Low dull backache
Menstrual-like cramps
Bleeding and spotting
46
Q

Higher risk for preterm labor (6)

A
Smoke/drugs
Carrying more than one baby
Poor nutrition
Underweight before pregnancy
Previous preterm deliveries
Infection
47
Q

Preterm Labor characteristics (4)

A
Gestation 20-37 wks
Persistent uterine contractions
   (4 every 20 mins or 8 per hour)
Cervical effacement at least 80%
Cervical dilation of more than 1 cm
48
Q

Tocolysis

A

Inhibit labor

49
Q

Treatment PTL…

If fetus is viable

If labor is progressing

A

Careful maternal monitoring & FHR monitoring
Identify and report symptoms of fetal hypoxia

If fetus viable:
hydrate, home on bedrest, no work, no sex, no distress, stress reduction

If labor is progressing:

  • > hydration
  • > tocolysis = Nifedipine, MgSO4, Propranolol
  • > corticosteroids = Dexamethasone, Betamethasone
50
Q

Hypertensive Disorders

A

Chronic hypertension
Present before pregnancy (therefore, in first trimester also)
Possibly undiagnosed before prenatal visits

Gestational/Transient [aka Pregnancy-induced hypertension]
Develops in 2nd trimester
Hypertension with no other symptoms

Preeclampsia –> eclampsia
Hypertension
Proteinuria

Chronic hypertension with superimposed preeclampsia

51
Q

Gestational Vs. Preeclampsia

A

High BP but no proteinuria

High BP and proteinuria

52
Q

Preeclampsia
Maternal Characteristics
Other 3 factors

A

Disease of placenta – 7-10% of pregnancies
Vasospasms Endothelial tissue damage
-> Delivery of fetus is the only cure

Second leading cause of maternal death - about 1/10-15 pregnancies

Maternal Characteristics
Age 35
Race – higher in African Americans
Socioeconomic status – lower asso. W/poor diets, increase in smoking
Primagravida 6-8 times more likely to develop PIH

Genetic predisposition , oxidative stress, and the release of immune factors cause placental dysfunction

53
Q

Preeclampsia
Symptoms
Medical Management

A

Symptoms
B/P > 140/90 @ 20 wks or more
Proteinuria
Sometimes: pitting pedal edema, facial edema

Medical Management

   - > stabilize blood pressure
   - > prevent eclampsia

nifedipine, hydralazine, labetolol
increased monitoring

54
Q

Eclampsia

A

Seizures and coma

Eclampsia is grand mal seizures as a result of the progression of preeclampsia
Eclampsia does not have a B/P correlation, or proteinuria, etc.
Mild pre can cause eclampsia

55
Q
Preeclampsia Maternal Complications
CNS -- 4
Hepatic -- 2
Renal --3 
Pulmonary --1
A
Maternal
CNS
Seizures
Cerebral Edema 
Cerebral Hemorrhage
Stroke (thrombosis)

Hepatic
Liver rupture or Failure
Subcapsular Hemorrhage

Renal
Renal Failure
Oliguria
Glomerulopathy

Pulmonary
Pulmonary Edema

56
Q

Preeclampsia Fetal Complications

5

A
Preterm Labor
Fetal Demise
Hypoxia
IUGR
Oligohydramnios
57
Q

Preeclampsia Severity

A

Mild
Systolic 140-160
Diastolic 90-110
Protein 3-5gm in 24

Severe
Systolic >160
Diastolic >110
Protein >5 gm in 24

58
Q

Medical Management – prevent eclampsia

Uncontrolled or high HTN

A
Bedrest
EFM
IVF  (NPO in case of c/s)
Antihypertensive therapy -- labetalol, hydralazine
Magnesium Sulfate -- To prevent seizures
Fetal gestation >34 wks –> deliver
Corticosteroids 

MgSO4 protocol = prevent overdose from resp failure and cardiac arrest

59
Q

Nursing Interventions
What is the focused assessment for a pt being tx with MgSO4?
7

A

Vital signs -> blood pressure, temperature, FHR

Neuro -> level of consciousness (A&Ox4), confusion, deep tendon reflexes, visual disturbances

Pain -> headache, epigastric pain

Respiratory -> respirations & sPO2, coughing, SOB, dyspnea, rales/rhonchi

Uterus/Placenta -> uterine rigidity, vaginal bleeding

Urine -> output, protein, specific gravity
Weight (daily), pedal edema

Labs
P/S -> emotional state, knowledge -> teaching

60
Q

For Magnesium Sulfate induced
Respiratory Depression or Respiratory Arrest,
institute Emergency Treatment:
TOXICITY

A

STOP Magnesium Sulfate infusion immediately.
Oxygen at 10LPM via face mask
GIVE Calcium Gluconate 1 Gram slow IVP
(in Pre-eclampsia tray or Crash cart)
Continuous Pulse Oximetry and ECG monitors
Contact anesthesia for airway management (Rapid Response)

61
Q

HELLP Syndrome

Symptoms (3)
What does it lead to?
Treatment?

Delivery?

A

Hemolysis, Elevated Liver enzymes and Low Platelets
Variant or Complication of Preeclampsia

Flu-like symptoms
Epigastric pain from distended liver
Jaundice

Multiple system organ failure

FFP or platelet transfusion
Delivery ASAP

62
Q

HELLP Syndrome
Hemolysis, Elevated Liver enzymes and Low Platelets

Platelet Count

A

Platelets 100,000

AST > 70

ALT > 50

63
Q

Danger signs – third trimester

A

Vaginal bleeding; Abdominal pain Fundal height; Leaking amniotic fluid; Absence of fetal movement; Glycosuria; HTN/Proteinuria; Abnormal fetal heart rate

Perinatal infection
Hypoxia
Fetal compromise
PROM
PTL
Preeclampsia
HELLP
Placenta Abruptio
Placenta previa
64
Q
Thrombophlebitis
     Deep Vein Thrombus
          Thromboembolism
            Pulmonary Emboli
Increased risk during pregnancy -- 4
A

Increased blood volume
Venous stasis in legs
Hypercoagulation
Compression of inferior vena cava in 3rd trimester

Teaching: encourage walking discourage sedentary activities

65
Q

Chronic Infections

GBS

A

“GBS+ (Group Beta Strep) is the leading infectious cause of neonatal morbidity and mortality in the US” (CDC2010)

All pregnant women are screened between
35-37 wks gestation via vaginal swab
If culture is positive, IV antibiotics are
administered at delivery

66
Q

Chronic Infections

HIV

A

HIV
Compliance with antiretroviral regimen
Retesting at 34-36 wks

Nursing Diagnoses
Ineffective Health Maintenance
Interrupted Family Processes
Risk for Infection
Nursing Interventions?
Prenatal
Intrapartum
67
Q

Acute Infections

A
Respiratory
URI, Tb 
UTI
Chorioamnionitis
	-> Septicemia
68
Q

Hemorrhagic Disorders: Placenta Previa
Dx
Symptoms
Medical management

A

Implantation of placenta near or obstructing the cervical os
Dx – prenatal ultrasound

Painless bright red vaginal bleeding in third trimester
Presenting part – not engaged
Possibly transverse lie

Medical Management
No vaginal examinations!
-> c/s
-> NSVD possible for high partial

69
Q

Hemorrhagic Disorders: Abruptio Placenta
Dx
Symptoms
Medical Management

A

Separation of the placenta from the uterine wall
Dx – ultrasound, clinical presentation

Severe pain and dark vaginal bleeding in third trimester
Not in labor or
Labor could be progressing normally

 Medical Management
 -> c/s  EMERGENCY
 -> NSVD possible
If in labor
If minimal bleeding
If hemodynamically stable
No uterine tenderness
No fetal distress
70
Q

Hemorrhagic Disorders: Complications

A

Hemorrhage
Disseminated Intravascular Coagulation (DIC)
clotting disorder: low fibrinogen –> bleeding from every orifice
Fetal hypoxia, Fetal demise
Postpartum risk:
lack of contractions in lower uterus -> postpartum hemorrhage