Antenatal Complications Flashcards

1
Q

What are the causes of abdominal pain in early pregnancy (<24 weeks)?

A
  • Ectopic pregnancy
  • Miscarriage
  • Round ligament pain
  • Acute urinary retention due to retroverted uterus
  • Pregnancy-unrelated causes (e.g., Uterine/Ovarian causes, GI disorders, Urinary issues, Medical causes)

Includes conditions like ovarian torsion, constipation, gastric/duodenal ulcer, renal colic, and sickle cell disease.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the signs and symptoms associated with miscarriage?

A
  • Lower abdominal dull ache to severe continuous or colicky pain
  • Vaginal bleeding is present in most cases
  • Positive urine pregnancy test, pelvic examination, and USS are helpful in diagnosis

USS refers to ultrasound scanning.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the key characteristics of ectopic pregnancy?

A
  • Usually unilateral lower abdominal pain at <12 weeks gestation
  • Associated with brownish vaginal bleeding
  • Shoulder tip pain suggests haemoperitoneum
  • Diagnosis: serum hCG, USS, and laparoscopy

hCG refers to human chorionic gonadotropin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What typically causes round ligament pain during pregnancy?

A

Stretching of the round ligaments

Occurs in 20–30% of pregnancies, commonly in the 1st and 2nd trimester.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the management for constipation during pregnancy?

A
  • High-fibre diet
  • Osmotic laxatives
  • Glycerin suppositories

Progesterone slows gut peristalsis, leading to constipation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the signs and symptoms of uterine rupture?

A
  • Tenderness over sites of previous uterine scars
  • Foetal parts may be easily palpable
  • Vaginal bleeding may be evident
  • Signs of maternal shock may be present
  • CTG may show foetal distress

CTG refers to cardiotocography, a method of monitoring fetal heart rate.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is oligohydramnios and how is it diagnosed antenatally?

A
  • Amniotic fluid index (AFI) <5th centile for gestational age or <8cm
  • Deepest vertical pool (DVP) <2 cm

Oligohydramnios indicates too little amniotic fluid.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the major causes of oligohydramnios?

A
  • Renal agenesis
  • Urinary tract abnormality/obstruction
  • IUGR and placental insufficiency
  • Maternal drugs (e.g., NSAIDs)
  • Post-dates pregnancy

IUGR refers to intrauterine growth restriction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the complications associated with oligohydramnios?

A
  • Pulmonary hypoplasia
  • Limb deformities (contractures, talipes)
  • Renal agenesis, multicystic kidneys, and urinary obstruction are lethal

These conditions are incompatible with life.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is polyhydramnios and how is it defined?

A

AFI >95th centile or >20 cm or DVP >8

Polyhydramnios indicates excessive amniotic fluid.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the potential causes of polyhydramnios?

A
  • Maternal diabetes
  • Chorioangioma
  • Multiple gestation and twin-twin transfusion syndrome
  • Foetal hydrops
  • Oesophageal atresia/tracheoesophageal fistula

Conditions like duodenal atresia and certain neuromuscular conditions can also contribute.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the normal fetal movement (FM) patterns?

A
  • 10 FM in 2 hours
  • FM can be felt from 16 weeks for multips; ≥20 weeks for primips
  • Peak FM occurs in the afternoon, evening, and post-meals
  • FM increases until 32 weeks, then stabilizes

Primip refers to a woman who is giving birth for the first time.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are some maternal causes of reduced fetal movement?

A
  • Infection
  • Malnutrition
  • Dehydration
  • Alcohol
  • Drugs
  • Position
  • Adiposity
  • Perception
  • Activity
  • Smoking

IM refers to intrauterine maternal factors.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the definition of PROM?

A

Prelabour Rupture of Membranes: leakage of amniotic fluid in the absence of uterine activity

PROM can occur in three groups based on gestational age.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the classifications of caesarean sections?

A
  • Category 1: Immediate threat to life
  • Category 2: No immediate threat to life
  • Category 3: Requires early delivery
  • Category 4: At a time to suit the woman and maternity services

These categories help prioritize surgical interventions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the major indications for a caesarean section?

A
  • Previous caesarean section
  • Malpresentation (mainly breech)
  • Failure to progress in labour
  • Suspected foetal compromise in labour

Other less common indications include multiple pregnancy and placental abruption.

17
Q

What are the signs and symptoms of labour?

A
  • Regular painful contractions or vague abdominal pain
  • Consider a vaginal examination in pregnant women with abdominal pain

Labour can sometimes be mistaken for other abdominal pains.

18
Q

What is the definition of PROM?

A

PROM is defined as pre-labour rupture of membranes before 37 weeks gestation.

Prolonged ROM is considered when it lasts more than 18 hours.

19
Q

What is the recommended timing for delivery if the fetus is less than term?

A

Delivery should wait until 36/37 weeks before delivery, with 34/40 being the earliest.

This is especially crucial for ensuring lung maturity.

20
Q

What are some potential aetiologies of PROM?

A
  • Unknown
  • Clinical or subclinical infection
  • Polyhydramnios
  • Multiple pregnancy
  • Malpresentation

Always inquire about urinary tract infections in the history.

21
Q

What should be done if a cesarean section is planned before 39 weeks?

A

Administer steroids to aid in fetal lung maturity.

This is because the baby’s lungs do not get squeezed to expel fluids as they would in spontaneous vaginal delivery (SVD).

22
Q

What is the management approach for term PROM?

A
  • Expectant management vs. induction
  • 90% will go into spontaneous labor within 48 hours
  • Induce if there are signs of infection
  • Use prostaglandin for unfavorable cervix
  • Early oxytocin decreases infection rate without increasing C-section rate

Consideration of risks and benefits is crucial in management.

23
Q

What are the risk factors for PPROM?

A
  • African origin
  • Antepartum hemorrhage
  • Cerclage
  • Polyhydramnios
  • Multiple pregnancy
  • Previous preterm delivery
  • STDs
  • Smoking
  • Low socioeconomic background

A comprehensive understanding of risk factors aids in prevention and management.

24
Q

What are the signs to diagnose PPROM?

A
  • Sudden, unprovoked large loss of fluid PV
  • Liquor color
  • Pain or contraction
  • Systemic illness signs (chills/fever)

History and clinical examination are essential for accurate diagnosis.

25
Q

What investigations are used to confirm ROM?

A
  • Rapid immunoassay (Amnisure)
  • Nitrazine test (detects pH change)
  • FBC for leucocytosis
  • CRP
  • CTG
  • U/S for presentation, AFI, EFW, Doppler

These investigations help confirm and assess the severity of the rupture.

26
Q

What is the management protocol if delivery is imminent?

A
  • Inform neonatal team
  • IV benzylpenicillin for GBS coverage
  • MgSO4 if <32/40 for neuroprotection
  • Discuss mode of delivery and likely outcome
  • Keep digital examination to a minimum during labor

Minimizing interventions can prevent complications.

27
Q

What complications can arise from PPROM?

A
  • Neonatal death
  • Chorioamnionitis
  • Preterm delivery
  • Neonatal sepsis
  • Respiratory distress syndrome (RDS)
  • IVH
  • Chronic lung disease

Understanding potential complications aids in proactive management.

28
Q

What is the definition of preterm labor?

A

Preterm labor is defined as the onset of labor before 37 weeks gestation.

Classifications include extreme prematurity (<28 weeks), severe prematurity (28-31+6 weeks), and premature (32-33+6 weeks).

29
Q

What are some maternal risk factors for preterm labor?

A
  • Lower socioeconomic status
  • Smoking
  • Low pregnancy weight (<55kg)
  • Maternal age (<18 or >40 years)
  • Poor nutrition

Identifying these risk factors can guide preventive measures.

30
Q

What are the main neonatal complications associated with prematurity?

A
  • Neonatal death
  • Respiratory distress syndrome
  • Necrotizing enterocolitis
  • Intraventricular hemorrhage (IVH)
  • Infection
  • Jaundice
  • Hypothermia
  • Hypoglycemia

Long-term complications may include developmental delays and chronic health issues.

31
Q

What is the mechanism of preterm labor?

A
  • Cervical weakness
  • Infection
  • Decidual hemorrhage
  • Uterine distension
  • Maternal illness
  • Fetal stress

Understanding these mechanisms can inform treatment and preventive strategies.

32
Q

What is foetal fibronectin (fFN) and its significance?

A

fFN is an ECM glycoprotein found in cervicovaginal secretions, indicating increased risk of delivery within 7 days if detected after 24 weeks.

It is a useful marker for predicting preterm labor.

33
Q

What are the contraindications for tocolysis?

A
  • Severe hemorrhage
  • Abruption
  • Severe pre-eclampsia
  • Chorioamnionitis

Recognizing contraindications is essential for safe management.

34
Q

What is the role of corticosteroids in preterm labor management?

A

Corticosteroids, such as betamethasone, improve neonatal outcomes by accelerating lung maturity and reducing risks of RDS and NICU admissions.

They are recommended for women at risk of preterm labor between 24-34 weeks.

35
Q

What is Group B Streptococcus (GBS) associated with?

A

GBS is associated with preterm prelabour ROM and preterm delivery, with early onset GBS infection having a ~20% mortality rate.

It can present with pneumonia, septicaemia, or meningitis.

36
Q

What are the risk factors for GBS infection?

A
  • Previous GBS infected baby
  • GBS bacteriuria during current pregnancy
  • Maternal temperature >38ºC
  • Prematurity
  • Prolonged rupture of membranes (>18h)

Identifying risk factors helps in the management and prevention of GBS infections.

37
Q

GBS Antbx

A

Antibiotic Prophylaxis
 IV benzylpenicillin 3g stat dose followed by 1.5g IV q4h
until delivery
 Penicillin allergy: clindamycin 900mg IV q8h until
delivery