ANS Pharm

Question 1

Drug Target Activity

Answer 1

To initiate effect in cell, drug or natural ligand combines with a molecular receptor on the cell surface

Question 2

Efferent portion of nervous system

Answer 2

Somatic: consciously controlled actions (mvmt, respiration, posture)

ANS: Sympathetic and parasympathetic

Question 3

Parasympathetic NT and receptors

Answer 3

NT: ACh

Receptor: nAChR, MAChR

Question 4

Sympathetic NT and Receptor

Answer 4

NT: NE, Epi, DA, ACh

Receptor: alpha, beta, nAChR, mAChR

Question 5

Acetylcholine

Answer 5

The major NT of the parasympathetic nervous system

All preganglionic autonomic fibers

All postganglionic parasympathetic fibers

Few postganglionic sympathetic fibers (sweat glands)

Question 6

Norepinephrine

Answer 6

The major NT of the sympathetic nervous system

The vast majority of postganglionic sympathetic fibers

Question 7

Epinephrine

Answer 7

Synthesis only occurs in the adrenal medulla and in a few epinephrine-containing neuronal pathways in the brainstem

Question 8

Dopamine

Answer 8

NE and Epi precursor

Acts on the CNS adn renal vascular smooth muscle

Question 9

Cholinergic Neurotransmission

Answer 9

ACh synthesis
Ach storage
Ach release
ACh destro