ANS Neurotransmitters and Receptors Flashcards
Cholinergic neurons
release neurotransmitter acetylcholine(ACh)
- include all sympathetic and parasympathetic preganglionic neurons.
- sympathetic postganglionic neurons that innervate most sweat glands.
- all parasympathetic postganglionic neurons.
How is ACh stored and released?
stored in synaptic vesicles and released by exocytosis.
cholinergic receptors
internal membrane proteins that bind with ACh across synaptic cleft.
How many types of cholinergic receptors are there?
Two
- nicotinic
- muscarinic
Nicotinic receptors
present in plasma membranes of chromaffin cells of the adrenal medullae and in the motor end plate at the neuromuscular junction.
Muscarinic receptors
present in the plasma membranes of all effectors (smooth muscle, cardiac muscle, and glands)
Adrenergic neurons
release norepinephrine also known as noradrenalin. stored and released the same as ACh.
Agonist
agon = contest
a substance that binds to and activates a receptor, in the process mimicking the effect of a natural neurotransmitter or hormone.
Antagonist
anti = against
a substance that binds and blocks a receptor and preventing a natural neurotransmitter or hormone from exerting its effects.