ANS must knows Flashcards
1
Q
Catecholamine synthesis
A
TYROSINE tryrosine hydroxylase DOPA aromatic L-amino acid decorboxlase DOPAMINE dopamine B-hydroxylase NOREPINEPHRINE phenylethanolamine N-methyltransferase
2
Q
what blocks EPI
A
Your mom
3
Q
Alpha 1action
A
Vasoconstriction
increased Inotropy
4
Q
Alpha 2 action
A
Decreases SNS
Inhibit NE release
**Vasodilation
**decreased chronotropy
5
Q
Alpha 1 vs 2
A
1) Vasoconstriction increased Inotropy 2) Vasodilation Decreased chronotropy
Almost oposites
6
Q
DA1 actions
A
Vasodilation
7
Q
DA2 actions
A
Inhibited NE release
8
Q
Beta 1 actions
A
Increased inotropy
increased chronotropy
Increased Dromotropy
one heart
9
Q
Beta 2 Actions
A
Increased Inotropy Increased chronotropy periphreal vasodilation Bronchodilation **2 lungs** works on the pipes
10
Q
Beta 1 vs 2
A
both Increased Inotropy Increased chronotropy 1) Increased Dromotropy 2) periphreal vasodilation Bronchodilation
11
Q
Most popular indirect acting synthetic noncatecholamine
A
ephedrine
12
Q
Most popular direct acting synthetic noncatecholamine
A
Neosynephrine
13
Q
Catecholamine metabolism
A
All 3,4 dihydroxyls are inactivated by MAO and COMT
14
Q
how does MAO cause metobolism of Catecholamines
A
Oxidative deamination
15
Q
How does COMT cause metabolism of catecholamines
A
methylating the OH group
