ANS Drugs Flashcards
What are the 4 adrenergic receptors?
a1 a2 b1 b2
what second messengers does a1 act on?
IP3
DAG
what second messenger does a2 act on?
cAMP (decrease)
what second messenger does b1 act on?
increase cAMP
what second messenger does b2 act on?
increase cAMP
where are a1 receptors found?
blood vessels
GI sphincters
where are a2 receptors found?
presynaptic terminal
where are b1 receptors found?
heart
where are b2 receptors found?
airway
GI
urogenital
pseudoephedrine
a1 agonist
prazosin
a1 antagonist
clonidine
a2 agonist
isoproterenol
b agonist
dobutamine
b1 agonist
terbutaline
b2 agonist
propanolol
b antagonist (1st generation)
epinephrine
non selective agonist
cocaine
non-selective sympathomimetic
amphetamine, ritalin, MDMA
non-selective sympathomimetics
selegiline (w/ Levadopa)
monoamine oxidase inhibitor
anti-parkinson’s disease
phenelzine
monoamine oxidase inhibitor
anti-depressant
amitriptyline
tricyclic antidepressant
phenylephedrine
a1 agonist
albuterol
b2 agonist
short acting bronchodilator
salbutamol (ventolin)
b2 agonist
short acting bronchodilator
salmeterol
b2 agonist
long acting bronchodilator
doxasin
a1 antagonist
tamsulosin
a1 antagonist
timolol
b antagonist (1st generation)
atenolol
b1 antagonist (2nd generation)
carvedilol
b antagonist (3rd generation) partial a receptor blockage
labetalol
b antagonist (3rd generation) partial a receptor blockage
neostigmine
acetylcholinesterase inhibitor
myasthenia gravis
donepezil
acetylcholinesterase inhibitor
alzheimer’s disease
atropine (belladonna)
cholinergic antagonist
neocitran
antihistamine
sympathomimetic
scopolamine
anti-nausea drug
tiotropium
long acting bronchodilator
jimson weed
anticholinergic
curare amazonian poison
non-depolarizing NMJ blocker
succinylcholine
depolarizing NMJ blocker