ANS Drugs Flashcards

1
Q

What are the 4 adrenergic receptors?

A

a1 a2 b1 b2

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2
Q

what second messengers does a1 act on?

A

IP3

DAG

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3
Q

what second messenger does a2 act on?

A

cAMP (decrease)

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4
Q

what second messenger does b1 act on?

A

increase cAMP

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5
Q

what second messenger does b2 act on?

A

increase cAMP

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6
Q

where are a1 receptors found?

A

blood vessels

GI sphincters

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7
Q

where are a2 receptors found?

A

presynaptic terminal

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8
Q

where are b1 receptors found?

A

heart

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9
Q

where are b2 receptors found?

A

airway
GI
urogenital

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10
Q

pseudoephedrine

A

a1 agonist

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11
Q

prazosin

A

a1 antagonist

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12
Q

clonidine

A

a2 agonist

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13
Q

isoproterenol

A

b agonist

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14
Q

dobutamine

A

b1 agonist

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15
Q

terbutaline

A

b2 agonist

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16
Q

propanolol

A

b antagonist (1st generation)

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17
Q

epinephrine

A

non selective agonist

18
Q

cocaine

A

non-selective sympathomimetic

19
Q

amphetamine, ritalin, MDMA

A

non-selective sympathomimetics

20
Q

selegiline (w/ Levadopa)

A

monoamine oxidase inhibitor

anti-parkinson’s disease

21
Q

phenelzine

A

monoamine oxidase inhibitor

anti-depressant

22
Q

amitriptyline

A

tricyclic antidepressant

23
Q

phenylephedrine

A

a1 agonist

24
Q

albuterol

A

b2 agonist

short acting bronchodilator

25
Q

salbutamol (ventolin)

A

b2 agonist

short acting bronchodilator

26
Q

salmeterol

A

b2 agonist

long acting bronchodilator

27
Q

doxasin

A

a1 antagonist

28
Q

tamsulosin

A

a1 antagonist

29
Q

timolol

A

b antagonist (1st generation)

30
Q

atenolol

A

b1 antagonist (2nd generation)

31
Q

carvedilol

A
b antagonist (3rd generation)
partial a receptor blockage
32
Q

labetalol

A
b antagonist (3rd generation)
partial a receptor blockage
33
Q

neostigmine

A

acetylcholinesterase inhibitor

myasthenia gravis

34
Q

donepezil

A

acetylcholinesterase inhibitor

alzheimer’s disease

35
Q

atropine (belladonna)

A

cholinergic antagonist

36
Q

neocitran

A

antihistamine

sympathomimetic

37
Q

scopolamine

A

anti-nausea drug

38
Q

tiotropium

A

long acting bronchodilator

39
Q

jimson weed

A

anticholinergic

40
Q

curare amazonian poison

A

non-depolarizing NMJ blocker

41
Q

succinylcholine

A

depolarizing NMJ blocker