ANS Drugs Flashcards
Epinephrine
Increase BP and Increase HR. Acts on all 4 adrenergic receptors. Produce its effect via IP3 (alpha 1) and via increased cAMP (beta receptors). āEā for Everything.
Norepinephrine
Increase BP and Decrease HR. Act on alpha receptors»_space; B1 receptors, hardly at all on B2 receptors.
Isoproterenol
Decrease BP and Increase HR. B1 and B2 agonist.
Phenylephrine
Increase BP and Decrease HR. Alpha agonist.
Phentolamine
Decrease BP and Increase HR. Alpha antagonist
Propranolol
Small decrease or no impact on BP. Decrease HR. Beta blocker (antagonist). Bad for people with asthma
Metoprolol
Decrease BP and Decrease HR. B1 antagonist
Acetylcholine
Decrease in BP and Decrease in HR. Works on the parasympathetic M receptors of the heart and blood vessels.
Nicotine
Increase BP and Increase HR
Atropine
No effect on BP and Increase HR. Blocks Muscarinic receptors and inhibits PS.
Hexamethonium
Decrease BP and Increase HR. Hypotension due to sympathetic block
Physostigmine
Little to no effect on BP and Decrease in HR. Increased ACh art M receptors of the heart will lower HR due to inhibition of AChE
Albuterol
Bronchodilation - beta 2 agonist.
Too much ACh
DUMBBELSS: diarrhea, urination, miosis, bronchospasms, bradycardia, emesis, lacrimation, salivation/sweating. Too much PS
Not enough ACh (atropine overdose)
Hot as a hare (sweat glands), blind as a bat (blurry vision), dry as a bone (stops salivary glands). red as a beet, and mad as a hatter (M receptors in the brain)
