ANS and Homeostatic Clinical Examples Flashcards
Define the ANS
Two-neuron chain connecting preganglionic neurons through ganglia to visceral target tissues
Components of sympathetic ANS
Cervical ganglia (superior, middle, stellate)
Paravertebral ganglia (thoracolumbar)
Prevertebral ganglia (celiac, superior mesenteric, inferior mesenteric)
Components of parasympathetic ANS
CN3 — eye
CN7 — lacrimal, palatine, and submandibular
CN9 — parotid
CN10 — cardiopulm, GI
Sacral (S2, S3, S4) — colon, rectum, GU
What are paraganglia?
Extrasuprarenal aggregations of chromaffin tissue — abdominal, adrenal, and paraspinal
Synthesize and store catecholamines
[pheochromocytoma sxs = HA, sweating, and tachycardia]
Distribution of sympathetic vs. parasympathetic in terms of vascular and visceral supplies
Sympathetic: vascular includes fascia, smooth muscle and sweat glands + trunk and extremities; visceral includes smooth muscle, cardiac, nodal and glandular tissue in thoracoabdominopelvic cavity
Parasympathetic: no extremities! Visceral — same as sympathetic but also in viscera of head and neck
What is meant by “allostatic load”?
Frequent activation of allostatic systems — continuation of feedback pathways meant to reestablish normal homeostasis
Longterm exposure may cause atrophy of hippocampus affecting feedback, memory, and autonomic function
[allostasis = adaptation in the face of potentially stressful challenges involves activation of neural, neuroendocrine and neuroendocrine-immune mechanisms]
A facilitated segment is also known as somatic dysfunction — what are 2 hallmarks of a facilitated segment?
Lowered neuronal threshold
Hypersensitivity of receptive fields
Goals of OMT in reestablishing homeostasis
Reduce allostatic load by balancing ANS
Reduce postural strain
Improve biomechanics of gait
Remove obstructions to fluid flow and drainage, augment fluid flow
Improve biomechanics of respiration
Optimize tissue healing and homeostatic reserve
Limbic system —> hypothalamus —> sympathetic nervous system —> ???
SNS —> lateral horn of the thoracolumbar spinal cord —> paravertebral and prevertebral ganglia —> end organ
Limbic system —> hypothalamus —> parasympathetic nervous system —> ???
PNS —> brainstem nuclei and lateral horn of sacral SC —> organ ganglia —> end organ
Thoacolumbar (T1-L2) system arising from the intermediolateral cell column of the lateral horn of the SC acting through chain ganglia and collateral ganglia
SNS
Craniosacral system arising from brainstem nuclei associated with CNs III, VII, IX, and X and from the intermediate gray in the S2-S4 SC
PNS
Sympathetic innervation of head/neck, heart/lungs, and upper GI
Head/Neck = T1-4
Heart lungs = T1-6
Upper GI = T5-9
Sympathetic innervation of small intestine+right colon, appendix, and left colon+pelvis
Small intestine+right colon = T10-11
Appendix = T12
L colon/pelvis = T12-L2
Sympathetic innervation of adrenals, GU tract, and upper/lower ureter
Adrenals = T10-T11
GU tract = T10-L2
Upper/lower ureter = T10-11/T12-L2
Sympathetic innervation of bladder and upper/lower extremities
Bladder = T12-L2
Extremities upper/lower = T2-8, T11-L2
Parasympathetic innervation of vagus n. (CN X) involves what structures?
Heart, lungs, thyroid, carotids
Upper/middle GI, liver
Kidney, upper ureter
Ovaries/testes
S2-4 Pelvic splanchnic nn. of parasympathetic nervous system innervate what structures?
Lower GI, uterus/cervix, penis/clitoris
Lower ureter, bladder
Assessment of sympathetics
Appropriate spinal levels
Paraspinal muscle spasms
Rib restrictions
Distant ganglia — cervical, celiac, mesenteric
Parasympathetic assessment
Vagus — look for condylar compression, OM suture restrictions, OA/AA SDs
Sacrum (S2-4) — sacral somatic dysfunction
Define somatic dysfunction
Impaired or altered function of related components of the somatic (body framework) system: skeletal, arthrodial, myofascial structures, and their related vascular, lymphatic, and neural elements
Important people = J.S. Denslow, DO, and Irvin Korr, PhD
Define spinal facilitation
The maintenance of a pool of neurons in a state of partial or subthreshold excitation; in this state, less afferent stim is required to trigger discharge of impulses
Facilitation may be d/t sustained increase in afferent input, aberrant patterns of afferent input, or changes within affected neurons themselves or their chemical environment — once established, facilitation can be sustained by normal CNS activity