ANS Flashcards
Brain—>Organs
Organs—>Brain
Efferent neurons
Afferent neurons
Second major class of receptors, includes steroid hormones estrogens corticosteroids VitD etc.
Transcription regulators
These receptors include growth factors, tumor necrosis factor, serine/threonin kinase, neurotropins and cytokines
1-Transmembrane proteins
Types of ion channels?
Voltage gated: Na, Ca, K
Transmitter gated: Neurotransmitter interact with specific receptors
The largest types of pharmacological receptors inc. ACh, M, NE Angiotensin etc
Seven trans membrane proteins:
G protein coupled receptors
NT of peripheral nerv sys Nm junction, PSNS, visceral motor nuclei and basal nucleus of Meynert
Acetylcholine ACh
Epinephrine NT is found where?
Adrenal medulla
NT of post gang. sympathetic neurons and CNS role in anxiety states, panic attacks, depression
NE
Dopamine NT characteristics.
G protein linked reception is depleted in PD and is increased in schizophrenia
- NT gated ion channel, permeable for Na, K ions.
- for Cl ions, major inhibitory NT in the CNS.
- Serotonin (5HT)
- y aminobutyric acid (GABA)
Major excitatory NT. Uses receptors, of all wc are transmitter gated ion channels that are permeable to Na K and Ca. For learning, memory and stress response
Glutamate: uses rors
N-methyl-D-aspartate (NMDA), kainite or quisqualate
Major inhibitory NT in the spinal cord, ion channel gates wc is permeable to Cl ion, the aa with no chiral carbon.
Glycine
