ANS Flashcards
Quarternary amine compounds
1-acethylcholine (PNS prototype)
2-Carbachol (DA cholinergic agonist)
3-Neostigmine (IA cholinergic agonist)
4-Edrophonium(IA cholinergic agonist)
5-No Depolarizing Competitive blocker
ER pt with a high IOP is given
Pilocarpine
Glaucoma TX and Miosis during surgery
Carbachol
Used with cimevelin to treat Sjögren dx and used in TX of xerostomia
Pilocarpine
No nicotinc activity(addition of methyl grp) and treat atony in certain organs
Drug that treat atony and antidote of atropine overdose 3th amine
Physostigmine
TX MG and antidote for competitive NMBA
Neostigmine
Ambenonium is TX of chronic MG and long duration of action 4-8 hrs similar to
Pyrodostigmine
Cite AL Zahaimar TX and the first to use
The first to use is Tacrine(hepatotoxicity)
Others like donepazil,rivastigmine and galantamine(primary AE is GI distress)
TX open angle glaucoma and not reversed by Pralixodime after loss of alkyl grp lot of SE
Irreversible organophosphate Echotiophate
Antidote of muscarinic agents
Atropine and Diazepam
Shorter acting antagonist replacing atropine in medriasis and cycloplegic effect
Cyclopentolate tropicamide
TX motion sickness more efficient in CNS with longer duration of action
Scopalamine also block short time memory and post operative nausea and vomiting
Who is used more frequent ipratropium or tiotropium
Tiotropium
TX EPS and Parkinson
Benzotropine and trihexyophenedyl
