anomalies/embryology Flashcards
What are female genital anomalies associated with?
43% have renal agenesis
Both ovarian and testicular tissue
XX or XY
ovotesticular syndrome
Bilateral streak,
Phenotypically female
Mullerian structures
pure gonadal dysgenesis
Testes
No mullerian structures
heterogeneity in appearance
partial androgen insensitivity
one testis and one streak gonad
Mullerian structures
XO or XY
mixed gonadal dysgenesis
Early bifurcation of ureter results in?
partially duplicated ureter
Cephelad origin of ureteric bud off mesonephric duct results in?
ectopic ureter with complete duplication
Adynamic segment of distal ureter results in?
UVJ obstruction
persistent chwalla membrane results in?
ureterocele
Failure of contact of ureteric bud w/ mesonephric duct?
Renal genesis associated with absent vas
Abnormal contact of ureteric bud w/ mesonephric duct?
renal dysplasia
Where does upper pole of duplicated system insert?
Inferior and medial
Comes off ureteric bud late
Where does lower pole of duplicated system insert?
Superior and lateral
Comes off ureteric bud early
XY
No Mullerian structures
Developed Wolffian structures
Elevated T at puberty
5 alpha reductase deficiency
XY
phenotypic female
testes present
no female internal organs
complete androgen insensitivity
What tumor is like to result from unremoved gonads in CAIS?
seminoma
Who is at risk for development of gonadoblastoma?
gonadal dysgenesis (mixed, pure, turner’s, partial)
What happens if ureteric bud is too close to the urogenital sinus?
reflux
In girls w/ renal agenesis, what GU abnormality is common
Mullerian duct abnormalities (uterus, fallopian tubes, superior vagina)
What renal and GU anomaly are associated with multi cystic dysplastic kidney?
contralateral reflux
seminal vesicle or gartner duct cyst
