Anitdepressants Flashcards
Tricyclic
Block reuptake of norepinephrine and serotonin
‘feline’
Amitriptyline - Elavil
Imipramine - Tofranil
Do not admin with MAOIs or St. John’s wort
Avoid alcohol
Contraindicated with seizure disorder
SEs: sedation
SSRIs
Inhibits serotonin uptake
‘pram’ ‘ine’
Duloxetine - Cymbalta
Fluoxetine - Prozac
Sertraline - Zoloft
Escitalopram - Lexapro
Avoid alcohol
Monitor for serotonin syndrome in first 72 hr (agitation, confusion, hallucinations)
SEs: weight gain, sexual dysfunction, fatigue, drowsiness
MAOIs
Increases norepinephrine, dopamine, and serotonin by blocking MAO-A
Phenelzine - Nardil
Isocarboxazid
Tranylcypromine
Avoid tyramine and caution with antihypertensives
Contraindicated with SSRIs, tricyclics, HF, CVA, renal insufficiency
SEs: CNS stimulation, orthostatic hypotension, hypertensive crisis with tyramine and SSRIs and tricyclics