Animal-transmitted Diseases

Question 1

Pathogen
* Rhabdovirus
Reservoirs
* DomesticAnimals(e.g.dogs)
* WildAnimals(e.g.rats,skunks)
Transmission
* InfectedAnimalBite

This describes

Answer 1

Rabies

Question 2

Epidemiology + Pathology
* Virus in animal saliva
*Infects human host via animal bites
*Proliferates in the brain

Worldwide (per year) * 1,000,000treated * 50,000deaths
United States (per year) * 20,000treated
* 1-2deaths

This describes

Answer 2

Rabies

Question 3

Symptoms
* Excitation,anxiety,pupildilation * Excessivesalivation
Diagnosis
* LaboratoryAnalyses – Negri bodies
* Wildvs.DomesticAnimals

This describes

Answer 3

Rabies

Question 4

Treatment
* PassiveImmunization
– Anti-rabies virus antibodies
* ActiveImmunization – Rabies virus vaccine
* Passive+ActiveTherapynearly100%effective

This describes

Answer 4

Rabies

Question 5

Prevention
* Humans:
– Immunization
– High-risk individuals
* DomesticAnimals: – Immunization
* WildAnimals:
– Injected and oral vaccines

This describes

Answer 5

Rabies

Question 6

Pathogen
* Hantaviruses Reservoir
* Rodents(Mice,Rats,Voles)
Transmission
* InfectedAnimalFeces

This describes

Answer 6

Hantavirus Syndromes

Question 7

Epidemiology + Pathology
* Inhalationoffecaldustfrominfectedanimals * Proliferatesinthehumanbody
* HPS:HantavirusPulminarySyndrome – 453 cases (35% mortality) · United States
* HFRS:HemorrhagicFeverwithRenalSyndrome – 200,000 cases (1% mortality) · Russia and Asia

This describes

Answer 7

Hantavirus Syndromes

Question 8

Diagnosis
* Symptoms
– Fever, Muscle Pain
– Thrombocytopenia (decrease in platelets) – Leukocytosis (increase in leukocytes)
* LaboratoryTests
– Virus cultures, ELISA, PCR
Treatment
* Notreatmentorvaccinesavailable

This describes

Answer 8

Hantavirus Pulminary Syndrome

Question 9

Four Corners Outbreak (1993)
– Sin Nombre Hantavirus – 30% of local mouse
population infected
– 53 infected adults, 32 deaths (60% mortality)

Yosemite Outbreak (2012)
– Sin Nombre Hantavirus
– 10 infected adults, 3 deaths (30% mortality)

This describes

Answer 9

Hantavirus Pulminary Syndrome

Question 10

Biosafety Level 4 Viral Pathogens
* Hantaviruses
* Filoviruses – Ebola

This describes

Answer 10

Viral Hemorrhagic Fever (VHF)

Question 11

Pathogen
* Chlamydiapsittaci Reservoir
* Birds(parrots,poultry)
Transmission
* InfectedAnimalFeces * InfectedSaliva

This describes

Answer 11

Psittacosis · Parrot Fever

Question 12

Pathogen
* Chlamydiapsittaci Reservoir
* Birds(parrots,poultry)
Transmission
* InfectedAnimalFeces * InfectedSaliva

This describes

Answer 12

Psittacosis · Parrot Fever

Question 13

Epidemiology
* RarebutUnderestimatedDisease
– Less than 10 cases per year since 2010
* OccasionalOutbreaks
– Outbreak in 1929 affected 800 people
Pathology
* Inhalationoffecaldustfrompetsorpoultry
* Lunginfection(pneumonia)inseverecases – Causes death in rare cases

This describes

Answer 13

Psittacosis · Parrot Fever

Question 14

Diagnosis
* Symptoms
– Fever, Headache, Dry Cough (many others) – Similar to Other Respiratory Infections
* Molecular(PCR)Tests
Treatment and Prevention
* Antibiotics(e.g.Tetracycline)
* NoVaccineAvailable
* Awareness:SafeBirdandCageCare

This describes

Answer 14

Psittacosis · Parrot Fever