Animal Gas Exchange and Transport Flashcards

1
Q

Gas Exchange Basics

A
  • eukaryotic cells continually produce CO2 as a waste product, and require O2 as the terminal e- acceptor in mito for cellular respiration
  • multicellular eukaryotes use a system to exchange gases
  • gas exchange during respiration occurs primarily through diffusion (from high to low concentrations)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Partial Pressure

A

a measure of the concentration of each individual component within the overall mixture of gases
- the TOTAL pressure exerted by the mixture is the sum of the individual pressures of the mixture components

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

PP: Rate of Diffusion

A

the rate of diffusion is proportional to its PP within the total gas mixture
- a gas with strong PP gradient (high PP on one side + low on the other) diffuses faster than a gas will low PP gradient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

PP Formula

A

P = (Patm) x (% content in mixture)
- Patm is atmospheric pressure at given altitude
- Patm at sea level = 760 mm Hg
- as the altitude increases, the concentration of the gas does not change, but Patm decreases
- As a result, PP of each gas decreases as altitude increases
- these pressures determine gas exchange, or the flow of gas, in the system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Fick’s Law of Diffusion

A

Gasses move down their PP gradient; the rate of diffusion across a surface is controlled by:
- K (gas diffusion constant)
- A (area for gas exchange)
- P2-P1 (difference in PP of gas on either side of the diffusion barrier)
- D (the distance across which the gas must diffusion - thickness of the barrier)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Fick’s Law of Diffusion: FORMULA

A

( K X A X (P2-P1))/D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Best Conditions for Gas Diffusion

A
  • the area available for gas exchange is large
  • the PP difference is large
  • the distance required for the gas to travel is small
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Gas Exchange Evolution

A

optimized respiratory surfaces to have optimal gas diffusion conditions:
- respiratory surface maximizes SA to increase gas diffusion
- extremely thin, minimizing distance to cross
- capillaries bring blood to the surface for gas exchange; since the air in lungs has higher O2 than oxygen-depleted blood and low CO2, this concentration gradient allows for gas exchangw

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Respiratory Surface Complex

A

gas exchange in complex organisms involve 3 steps
1. VENTILATION: air is brought into the organ
2. GAS EXCHANGE: O2 is taken in + CO2 is expelled
3. CIRCULATION: gas is moved to and from the tissues via a circulatory fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Respiratory Surface Variation

A
  • Direct Diffusion
  • Skin
  • Trachea
  • Gills
  • Lungs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

RS: Direct Diffusion

A

many organisms can diffuse across their outer membrane
- every body cell is close to the external environment
- cells are kept moist
- flat shape of organism increases SA for diffusion
- ensures every cell is close to the outer membrane and has access to O2
- EX: Cnidarians

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

RS: Skin

A

used as a respiratory organ in annelids and amphibians; use a sense network of capillaries below the skin to facilitate gas exchange between the external environment and circulatory system
- must be moist for gases to dissolve and diffuse across cell membranes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

RS: Trachae

A

respiratory organs of insects, consisting of a network of small tubes that carries O2 to the entire body
- INDEPENDENT of the circulatory system; blood does not play a direct role in O2 transport
- gas passes directly to the needed tissues
- most direct repiratory system
some insects ventilate this system through body movements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Spiracles

A

opening in insect bodies that allow O2 to pass through the body + regulate diffusion of CO2 and H2O vapor
- air enters and leaves the tracheal system through these

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

RS: Gills

A

outgrowths of the body surface used for gas exchange + present in organisms that live in water (fish, mollusks, annelids, crustaceans)
- thin tissue filaments that are branched and folded
- water passes the gills + dissolved O2 enters into the bloodstream
- the CS can carry oxygenated blood to other body parts
- MOST EFFICIENT OF ALL RESPIRATORY SURFACES DUE TO COUNTERCURRENT EXCHANGE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Gills: Countercurrent Exchange

A

maximizes gas exchange across the length of the entire respiratory surface:
- because of the constant flow of gas across the gas-exchange membrane + constant PP difference, gills are the most efficient system in exchanging gases

17
Q

RS: Lungs

A

infoldings of the throat/body surface used for gas exchange
- present in both vertebrates and invertebrates

18
Q

Lungs: Amphibians

A

supplement gas exchange that occurs via the skin
- ventilated by POSITIVE PRESSURE, where air if forced into the lungs
- requires amphibians to gulp air into the mouth, close their mouth and nostrils, and raise the jaw to put air under high pressure and force it into a low pressure lung

19
Q

Lungs: Birds

A

under NEGATIVE PRESSURE - a vacuum is created by the movement of muscles in the chest which pulls air into the lungs
- most efficient of vertebrate lung systems because of: unidirectional airflow + cross-current exchange
- allows birds to obtain enough O2 during flight

20
Q

Bird Lungs: Unidirectional Airflow

A

accomplished by a series of air sacs that hold air first before and then after gas exchange occurs, so that exchange occurs both during inhalation + exhalation

21
Q

Bird Lungs: Cross-Current Exchange

A

between airflow and the bloodstream of the respiratory surface
- helps maintain a CG for more efficient exchange
- not as efficient as CCE in gills

22
Q

Lungs: Mammals

A

under NEGATIVE PRESSURE + are more efficient than amphibians but less than birds
- lack unidirectional airflow
- structure does not allow for a CC
- rely on a “web-like” flow that cannot maintain a CG
- contains “dead-space”
- gas exchange only occurs in small spaces called alveoli

23
Q

Mammal Lungs: Dead Space

A

locations containing inhaled air that does not take part in gas exchange

24
Q

Mammal Lungs: Alveoli

A

small sacs where a web-like arrangement of blood vessels come to close proximity to the inhaled air
- pathway to reach this includes the trachea, bronchi, and bronchioles, each part of the “dead space” of the lungs

25
Oxygen Transport
most of O2 enters the capillaries at the alveoli bound to HEMOGLOBIN in red blood cells
26
Hemoglobin
protein composed of 4 subunits - each having a central ions - containing a heme group that can bind to one O2 molecule - each hemoglobin can bind to 4 O2 molecules
27
Carbon Dioxide Transport
transported in the blood from body tissues to the lungs by 1/3 methods 1. dissolving directly into the blood 2. binding to hemoglobin 3. carried as bicarbonate ion
28
Bicarbonate Buffer System
most CO2 is transported as a bicarbonate ion: 1. CO2 diffuses into red blood cells 2. Co2 is converted into carbonic acid 3. carbonic acid is immediately dissociated into bicarbonate ions and protons 4. BBS allows for the continued uptake of CO2 into the blood down its CG since its quick - results in the production of H+ ions 5. Blood reaches lungs - bicarbonate binds with its proton and is converted into carbonic acid then CO2 6. CO2 diffuses out the blood into the lungs to be expelled during exhalation
29
Cooperative Binding
HEMOGLOBIN is very good at binding to the 2nd + 3rd O2 molecules compared to the first - caused by conformation change that increases binding - increase of PP of O2, the more hemoglobin becomes increasingly saturated with O2
30
Hemoglobin Dissociation Curve
- HIGHER Hb-O2 AFFINITY: low CO2, high pH, low temperature - LOWER Hb-O2 AFFINITY: high CO2, low pH, high temperature