Animal development 5 Flashcards
What are the 3 segments of drosophila?
Head
Thorax
Abdomen
How do the adult ectodermal structures develop?
From imaginal discs
What are imaginal discs?
Pads of undifferentiated cells in the larva
What is transdetermination?
Different structures being made
What is homeosis?
The transformation of one body part into another
What is antennapedia?
Antennae converted into legs
What is bithorax?
Anterior compartment of haltere transformed into an anterior wing
What is ultrabithorax?
Anterior and posterior compartments of haltere are enlarged
What is a homeotic gene/homeotic selector gene?
A gene that defines a region or position in the embryo
Mutations lead to transdetermination
What is a homeobox?
A region of DNA in homeotic genes that encodes a DNA binding domain called the homeodomain
What is a hox gene?
A family of homeobox-containing genes that are part of a homeotic gene complex
Not all homeobox genes are hox genes
What is the HOM-C complex?
Antennapedia and bithorax gene clusters
How are hox gene clusters thought to have arisen?
By tandem gene duplication
Explain the hox gene family
180 base pair homeobox encodes the homeodomain in the 60 amino acid encoded protein
The same sequence is found in all homeotic genes
