Angioedema Flashcards
1
Q
most common cause of angioedema?
A
idiopathic
- other causes are basically the same as for urticaria, with addition of hereditary angioedema
2
Q
What is the pathogenesis of angioedema with urticaria? Angioedema without urticaria?
A
- same as urticaria with excess histamine release
- for cases lacking angioedema and ACEI induced angioedema it is due to excess Bradykinin
3
Q
What labs to check in patient with angioedema w/o urticaria?
A
- C1 esterase inhibitor levels
- decreased C4 levels
- decreased C1q levels only in acquired angioedema!!!
4
Q
Type I and II hereditary angioedema are due to:
A
decrease in number or function of C1 esterase inhibitor
5
Q
Treatment of angioedema
A
- intensive supportive tx to ensure airway protection
- antihistamines
- epi-pen
6
Q
Treatment of C1 inhibitor deficiency angioedema?
A
Danazol
