Aneurysms and Vascular Disease Flashcards
What is PAD?
Thickening of the arteriole wall, causing narrowing/stenosis to the artery
What does PAD lead to?
Decreased perfusion of blood to the extremities
What is the leading cause of PAD?
Atherosclerosis
What are risk factors for PAD?
Tobacco use DM Hyperlipidemia Uncontrolled HTN Obesity Sedentary lifestyle Stress
How does tobacco contribute to PAD?
Nicotine is a potent vasoconstrictor
Impairs transport and cellular use of O2
Increases blood viscosities
What is a clinical manifestation of PAD?
Intermittent claudication (during exercise) - Cramping from decreased blood flow and muscles not receiving enough O2 -> anaerobic metabolism
What are some complications from PAD?
Amputation
Ulcers from decreased circulation
How is PAD diagnosed?
Doppler studies
Ankle-brachial indexes
Angiography
MRI testing
How is PAD treated?
Smoking cessation Exercise Maintaining an ideal body weight Reviewing diet Addressing BP issues Drug therapy - oral antiplatelet (Aspirin or Plavix) Surgery (bypass grafting)
What is venous thrombus disease?
Formation of clots in the venous system
What are the classifications of venous thrombus disease?
Superficial vein thrombosis
DVT
Venous thromboembolim
What is superficial vein thrombosis?
Formation of a thrombus in the superficial vein
Usually greater or lesser saphenous veins
What is DVT?
Thrombus in a deep vein
Usually in iliac or femoral vein
What is Virchow’s triad?
Three main contributing factors to the development of venous thromboembolism
Venous stasis
Damage of endothelium
Hypercoagulability of the blood
How does a patient with a venous clot present?
Lower extremity VTE may or may not have edema
May complain of tenderness on palpation
May have dilated superficial veins
May complain of a sense of fullness
Skin may be warm, reddened, or may have a temp >104
What diagnostic testing can be used for venous disease?
Duplex study Ultrasound Blood studies PTT, INR, bleeding time, HgB, HCt, platelet count CT scan venography MRI