Aneurysms Flashcards
Aneurysm definition
Permanent and irreversible localised dilation of a blood vessel
- At least 50% more than expected diameter.
Ectasia
Permanent, irreversible localised dilation of less than 50% of normal diameter
Arteriomegaly
Diffuse arterial enlargement without discrete aneurysm.
Most common locations of aneurysm
> 90% infra-renal abdominal
Aortic arch
Thoracic arch
Supra-renal abdominal aorta
Aetiology of aneurysms
Degenerative
Familial
Vasculitic
Connective tissue abnormality
Infective (mycotic)
Epidemiology of aneurysms
- Age
- Ethnicity
- Sex
M:F= 4:1
Familial, M:F= 2:1
Afro-Carribean= 0.53
Aneurysm classifications
True
- Dilation involves all layers
- Fusiform (AAA), saccular (berry)
False (Pseudo)
- Collection of blood that communicates with lumen. Between tunica media and the tunica adventitia.
- Cause: puncture, cannulation.
Dissection
- Dilation caused by blood separating apart the media
- Forms a channel with vessel wall.
Congenital causes of aneurysms
Autosomal dominant polycystic kidney disease (ADPKD)
- Berry aneurysms
Connective tissue abnormalities:
- Marfan’s
- Ehler’s danlos
Complications of aneurysms
Rupture
Thrombosis
Distal emoboli
Pressure
- DVT
- Oesophagus
- Nutcracker syndrome
Fistula
Nutcracker syndrome
Pressure complication of aneurysms
Compression of the left renal vein between the aorta and the superior mesenteric artery.
AAA presentation
Asymptomatic
Back/ umbilical pain radiating to groin
Acute limb ischaemia
Distal emboli: blue toe syndrome
Acute rupture:
- Expansile adominal mass
- Shock
- Severe abdo pain, radiating to back/ flank
Investigations for AAA
Imaging
- USS: monitors growth, identifies aneurysms
CR/MRI= gold standard
Management of AAA
- Conservative
- Open repair
- Endovascular (EVAR)
Screening for AAA
Screening occurs as it’s fairly common (5% males >65) with very high mortality rate if it ruptures (90%)
Men screen at 65
Conservative management of AAA
- Manage cardiovascular risk factors
- BP, cholesterol
Can be monitored if diameter <5cm.
- 3-4.4cm= yearly monitoring
- 4.5-5.4= 3 monthly