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Anesthesia Med Sheet everything Flashcards

1
Q

trade name for etomidate

A

amidate

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2
Q

trade name for ketamine

A

ketalar

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3
Q

trade name for methohexital

A

brevital

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4
Q

trade name for propofol

A

diprivan

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5
Q

trade name for midazolam

A

versed

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6
Q

trade name for dexmedetomidine

A

precedex

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7
Q

trade name for succinylcholine

A

anectine

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8
Q

trade name for mivacurium

A

mivacron

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9
Q

trade name for atracurium

A

tracrium

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10
Q

trade name for vecuronium

A

norcuron

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11
Q

trade name for rocuronium

A

zemuron

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12
Q

trade name for cisatracurium

A

nimbex

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13
Q

trade name for pancurion

A

pavulon

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14
Q

trade name for fentanyl

A

sublimaze

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15
Q

trade name for sufentanil

A

sufenta

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16
Q

trade name for remifentanil

A

ultiva

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17
Q

trade name for meperidine

A

demerol

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18
Q

trade name for ketolorac

A

toradol

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19
Q

trade name for hydromorphone

A

dilaudid

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20
Q

trade name for phenylephrine

A

neosynephrine

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21
Q

trade name for dopamine

A

intropin

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22
Q

trade name for dobutamine

A

dobutrex

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23
Q

trade name for glycopyrrolate

A

robinul

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24
Q

trade name for neostigmine

A

prostigmine

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25
trade name for physostigmine
antilirium
26
trade name for edrophonium
enlon
27
trade name for flumazenil
romazicon
28
trade name for naloxone
narcan
29
trade name for hydralazine
apresoline
30
trade name for labetalol
trandate
31
trade name for esmolol
brevibloc
32
trade name for ondansetron
zofran
33
trade name for droperidol
inapsine
34
trade name for dexamethasone
decadron
35
supplied dose of etomidate/amidate
2mg/ml
36
supplied dose of ketamine/ketalar
10mg/ml 50mg/ml
37
supplied dose of methohexital/brevital
10mg/ml
38
supplied dose of propofol/diprivan
10mg/ml
39
supplied dose of midazolam/versed
1mg/ml 5mg/ml
40
supplied dose of dexmedetomidine/precedex
200mcg/2ml
41
supplied dose of succinylcholine/anectine
20mg/ml
42
supplied dose of mivacurium/mivacron
2mg/ml
43
supplied dose of atracurium/tracrium
10mg/ml
44
supplied dose of vecuronium/norcuron
1mg/ml after diluted
45
supplied dose of rocuronium/zemuron
10mg/ml
46
supplied dose of cisatracurium/nimbex
2mg/ml
47
supplied dose of pancuronium/pavulon
1mg/ml or 2mg/ml
48
supplied dose of fentanyl/sublimaze
50mcg/ml
49
supplied dose of sufentanil/sufenta
50mcg/ml- dilute
50
supplied dose of remifentanil/ultiva
1-2mg/ml-dilute
51
supplied dose of merperidine/demerol
10mg/ml
52
supplied dose of ketorolac/toradol
30mg/ml
53
supplied dose of morphine
1-10mg/ml
54
supplied dose of hydromorphone/dilaudid
2mg/ml
55
supplied dose of ephedrine
50mg/ml- dilute to 5 or 10 mg/ml
56
supplied dose of phenylephrine/neosynephrine
10mg/ml- dilute to 100mcg/ml
57
supplied dose of epi
1:1000 (1mg/ml) 1:10,000 (0.1mg/ml)
58
supplied dose of dopamine/intropin
40mg/ml
59
supplied dose of dobutamine/dobutrex
250mg/20ml
60
supplied dose of atropine
0.4mg/ml 1mg/ml (amp)
61
supplied dose of glycopyrrolate/robinul
0.2mg/ml
62
supplied dose of bridion/sugammadex
100mg/ml
63
trade name of sugammadex
bridion
64
supplied dose of neostigmine/prostigmine
1mg/ml
65
supplied dose of physostigmine/antilirium
1mg/ml
66
supplied dose of edrophonium/enlon
10mg/ml
67
supplied dose of flumazenil/romazicon
0.1mg/ml
68
supplied dose of naloxone/narcan
0.4mg/ml
69
supplied dose of hydralazine/apresoline
20mg/ml
70
supplied dose of labetalol/trandate
5mg/ml
71
supplied dose of esmolol/brevibloc
10mg/ml
72
supplied dose of ondansetron/zofran
2mg/ml
73
supplied dose of droperidol/inapsine
2.5mg/ml
74
supplied dose of dexamethasone/decadron
4mg/ml
75
induction dose of etomidate/amidate
0.2-0.4mg/kg
76
induction dose of ketamine/ketalar
1-2mg/kg IV 4-8mg/kg IM
77
induction dose of methohexital/brevital
1mg/kg
78
induction dose of propofol/diprivan
2-2.5mg/kg
79
induction dose of midazolam/versed
usually 1-5 mg or 0.01-0.1mg/kg (rice sheet) Apex says 0.1-0.4mg/kg induction and 0.01-0.1mg/kg is sedation
80
induction dose of dexmedetomidine
load dose of 1mcg/kg over 10min maintenance 0.2-0.7 mcg/kg/hr
81
induction dose of succinylcholine/anectine
1-1.5 mg/kg IV 3-4mg/kg IM
82
induction dose of mivacurium
0.25mg/kg
83
induction dose of atracurium
0.4-0.5 mg/kg
84
induction dose of vecuronium
0.1mg/kg
85
induction dose of rocuronium
0.6-1.2 mg/kg
86
induction dose of cisatracurium
0.15mg/kg
87
induction dose of pancuronium
0.1mg/kg
88
induction dose of fentanyl
1-2mcg/kg
89
induction dose of sufentanil
0.1-0.5 mcg/kg
90
induction dose of remifentanil/ultiva
0.5-1mcg/kg/min
91
induction dose of merperidine
1mg/kg IV
92
dose of ketorolac
30mg IV 60mg IM
93
induction dose of morphine
0.1mg/kg
94
induction dose of hydromorphone
0.01-0.04mg/kg IV
95
dose of ephedrine
5-15 mg peds 0.1mg/kg
96
dose of phenylephrine
50-100mcg IV
97
dose of epi
2-20mcg/kg/min push dose: 10mcg IV
98
dose of dopamine
2-20mcg/kg/min
99
dose of dobutamine
2-20mcg/kg/min
100
dose of atropine
7mcg/kg with Enlon
101
dose of glycopyrrolate
5-8mcg/kg
102
dose of sugammadex/bridion
4mg/kg (no TOF pretetanic and 1-2 PTC) 2mg/kg (2 pretetanic twitches) 16mg/kg (reversal within 3 min, 1.2mg/kg roc dose)
103
dose of neostigmine/prostigmine
0.05mg/kg
104
dose of physostigmine/antilirium
0.5-1mg or 0.02mg/kg peds
105
dose of edrophonium/enlon
0.5-1mg/kg
106
dose of flumazenil/romazicon
0.2 mg over 15 sec
107
dose of naloxone/narcan
start 0.04mg IV; 0.04-0.4mg
108
dose of hydralazine
10mg increments
109
dose of labetalol/trandate
0.1-0.5 mg/kg
110
dose of esmolol/brevibloc
10-20mg increments
111
dose of ondansetron
4mg peds: 0.15mg/kg
112
dose of droperidol/inaspine
PONV 0.625-2.5mg
113
dose of dexamethasone/decadron
4-8mg peds 0.5 mg/kg
114
etomidate onset peak DOA
onset: 30s peak: 1min DOA: 3-10min
115
ketamine onset peak DOA
onset: 30 sec peak: 1min DOA: 5-15min
116
methohexital/brevital onset peak DOA
onset: 30s peak: 30s DOA: 5-10 min
117
Propofol onset peak DOA
onset: 1 min peak: 1 min DOA: 5-10 min
118
midazolam onset peak doa
onset: 1 min peak: 4 min DOA: 15-20 min
119
succinylcholine onset peak doa
onset: 1 min peak: -- DOA: 5-10 min
120
mivacurium onset peak doa
onset: 2-3 min peak:-- DOA: 20-30 min
121
atracurium onset peak doa
onset: 3-5 min peak: -- DOA: 30-60 min
122
vecuronium onset peak doa
onset: 3-5 min peak: -- DOA: 30-60 min
123
rocuronium onset peak doa
onset: 1-2 min peak: -- DOA: 30-60 min
124
ciastracurium onset peak doa
onset: 3-5 min peak: -- DOA: 30-60 min
125
pancuronium onset peak doa
onset: 3-5 min Peak: -- DOA: 60-90 min
126
fentanyl onset peak doa
onset: 30 sec peak: 5-15 min DOA: 30-60 min
127
sufentanil onset peak doa
onset: 1-3 min peak: 3-5 min DOA: 20-45 min
128
remifentanil onset peak doa
onset: 30s peak: -- DOA: 5-10 min
129
merperidine onset peak doa
onset: 1 min peak: 5-20 min doa: 2-4 hrs
130
ketorolac onset peak doa
onset: 30s peak: 1-2 hr doa: 4-6 hr
131
morphine onset peak doa
onset: 1-5 min peak: 5-20 min doa: 2-7hr
132
hydromorphone onset peak doa
onset: 10-15 min peak: 15-30 min doa: 2-3 hrs
133
ephedrine onset peak doa
onset: 30s peak: 2-5 min DOA: 10-60 min
134
phenylephrine onset peak doa
onset: 20s peak: 1 min doa: 15-20 min
135
epinephrine onset peak doa
onset: 30s peak: 3 min DOA: 10 min
136
dopamine onset peak doa
onset: 2 min peak: 10 min DOA: 10-20 min
137
dobutamine onset peak and doa
onset: 2 min peak: 1-10 min doa: 40min
138
atropine onset peak doa
onset: 1 min peak: 2 min DOA: 1 hr
139
glycopyrrolate onset peak doa
onset: 2-3 min peak: 5 min DOA: 1-2 hr
140
neostigmine onset peak doa
onset: 3-5 min peak: 7 min DOA: 1-2 hrs
141
physostigmine onset peak doa
onset: 15 min peak: -- DOA: 2 hr
142
edrophonium onset peak doa
onset: 30-60s peak: 1 min DOA: 60 min
143
flumazenil onset peak doa
onset: 3 min peak: 10 min DOA: 45-90 min
144
naloxone onset peak doa
onset: 1-3 min peak: -- DOA: 1 hr
145
hydralazine onset peak doa
onset: 10-20 min peak:-- DOA: 3-6 hr
146
labetalol/trandate onset peak doa
onset: 5-10 min peak: -- DOA: 5-8 hrs
147
esmolol/brevibloc onset peak doa
onset: 2 min peak:-- DOA: 10-20 min
148
ondansetron onset peak doa
onset: 30 min peak: 2 hr DOA: 4-24 hrs
149
droperidol/inapsine onset peak doa
onset: 1-2 min peak: 20 min doa: 2-4 hr
150
dexamethasone onset peak doa
onset: <1 hr peak: 12-24 hr DOA: 36-54 hr
151
Etomidate S/E, metabolism and other
CV stable, less myocardial depression than propofol S/E: myoclonus/pain on injection, cv stable, epileptic foci METABOLISM: plasma esterases and hepatic enzymes; a single induction dose may inhibit 11 BH leading to adrenocortical suppression
152
ketamine S/E, metabolism and other
hallucinations increased CO increased HR increased salivation Maintains Bp analgesia metabolism: liver cyp450; redistribution
153
methohexital/brevital S/E, metabolism, other
porphyria do not give with asthma
154
propofol S/E, metabolism and other
pain on injection no use in egg/soy allergy antiemetic decreases CV metabolism: liver and lungs
155
midazolam S/E, metabolism and other
decreased respiration amnesia 1/2 life: 1-4 hrs H2O soluble benzo eliminated renal
156
dexmedetomidine info to know
alpha 2 agonist
157
succinylcholine S/E, metabolism, other
short-acting depolarizing can cause MH locks NA channel met: plasma pseudocholinesterase
158
mivacurium info to know
short-acting non depolarizing met: plasma cholinesterase can cause histamine release
159
atracurium info to know
intermediate acting nondepolarizing metabolism: hoffman/ ester hydrolysis can cause histamine release
160
vecuronium info to know
intermediate acting; nondepolarizing metabolism: liver>kidney high lipid solubility
161
rocuronium info to know
intermediate acting; nondepolarizing metabolism: liver >kidney painful on injection shortest acting NDNMB
162
ciastracurium info to know
intermediate acting; nondepolarizing met: hoffman/esterase hydrolysis
163
pancuronium info to know
long acting; nondepolarizing metabolism: renal increase HR- no NOREPI reuptake
164
fentanyl info to know
pulm 1st pass can cause rigid chest
165
sufentanil info to know
can cause rigid chest most potent pulm 1st pass
166
remifentanil info to know
metabolized by hydrolysis esterase ultra short acting 1/2 life: 6 min
167
meperidine info to know
metabolite = seizures no with MAOIs crosses placenta increase HR treats post op shivering
168
ketorolac info to know
bleeding/ inhibits COX
169
morphine info to know
can cause Nausea and vomitting most allergies: +histamine can cause biliary spasm
170
hydromorphone info to know
can cause N/V +histamine antitussive 1mg=7mg MSO4 (morphine sulfate)
171
etomidate MOA
GABA mimetic binds to GABA receptor and enhances receptors affinity for GABA
172
Ketamine MOA
non competitively binds to NMDA (glutamate receptor) inhibits glutamate receptor (excitatory)- decreases presynaptic release of glutamate and potentiates GABA release
173
methohexital MOA
barbituate acts on GABA receptors
174
propofol MOA
modulates GABA receptors increases transmembrane Cl- conduction- hyperpolarizes post-synaptic cell membrane sedation and hypnosis
175
midazolam MOA
Works on the GABA receptor To increases frequency of Cl-channel influx and hyperpolarizes targeted cell
176
MOA of dexmedetomidine
Alpha 2 agonist Binds with pre and postsynaptic alpha 2a agonist receptors Decreases norepi levels; causes sedation and analgesia Alpha 2 agonist Decreases cAMP which inhibits the locus coeruleus in the pons = sedation
177
MOA of succinylcholine
Binds to one or both alpha subunits of nicotinic ACh receptors and mimics action of ACh Depolarizes the membrane
178
MOA of mivacurium
binds competitively to cholinergic receptors to antagonize the action of ACh and cause neuromuscular blockade
179
MOA atracurium
reversibly competitive antagonism of ACh
180
MOA of vecuronium
reversibly competitive antagonism of ACh
181
MOA of rocuronium
reversibly competitive antagonism of ACh
182
MOA of cisatracurium
reversibly competitive antagonism of ACh
183
MOA of pancuronium
reversibly competitive antagonism of ACh
184
trade name of sugammadex
Bridion
185
supplied dose of sugammadex
100mg/ml
186
dose of sugammadex
4mg/kg (no TOF pretatanic and 1-2 PTC) 2mg/kg (2 pretetanic twitches) 16mg/kg (of 1.2mg/kg roc dose-reversal within 3 min)
187
info about ephedrine
direct/indirect beta and alpha 1 agonist can have tachyphylaxis dont give with fast HR dont give with MAOI does NOT decrease uterine blood flow
188
info about phenylephrine
alpha 1 agonist can cause reflex bradycardia (baroreceptor reflex)
189
info about epinephrine ( think hemodynamics)
direct beta1, beta2, alpha 1 agonist causes increased CO increased HR increased contractility increased SVR
190
info about dopamine
alpha1, beta1,beta2 and dopamine (renal perfusion) receptor agonist avoid with MAOIs 400mg/250ml bag= 1600mcg/ml
191
info about dobutamine
selective beta1 inotrope
192
info about atropine
increases HR causes mydriasis (pupil dilation) tertiary ammonium (crosses BBB)
193
info about glycopyrrolate
decreases secretions quaternary ammonium (DOES NOT CROSS BBB)
194
info about neostigmine
max dose 5mg cholinergic syndrome decreases HR hepatic metabolism
195
info about physostigmine
crosses BBB (tertiary amine) dont give with asthma renal excreted
196
info about edrophonium
do not give with glycopyrrolate renal excreted can diagnose MG true reversible
197
info about flumazenil
benzo antagonist repeat 0.2mg q 1min (3mg/hr max)
198
info about naloxone
reversal for opioids
199
info about hydralazine
Arteriole vasodilation causes increased cGMP increased HR increased CO decreases SVR increased RENIN DOC with normal to low HR (beta blockers preferred for HTN with increased HR)
200
info about labetalol
alpha, beta1, beta2 antagonist ratio 1:7 alpha to beta IV decreases HR, give slow
201
info about esmolol
beta1 antagonist metabolized by plasma hydrolysis t1/2 9min
202
info on ondansetron
5HT3 antagonist admin slowly to prevent headache
203
info about droperidol
paradoxical reaction( restless anxious) decreases BP change in dopamine in CNS (dont give with parkinsons)
204
info about dexamethasone
decreases inflammation decreases immunity
205
muscarinic effects
decrease HR bronchoconstriction increased salivation decreased BP MIOSIS (pupil constriction) intestinal spams
206
MOA of fentanyl
opioid mu receptor agonist
207
MOA of sufenta
opioid mu receptor agonist
208
MOA of ultiva/remifentanil
opioid mu receptor agonist
209
MOA of meperidine
synthetic opioid agonist at mu and kappa receptors
210
MOA of toradol
nonselective NSAID inhibits COX1 and COX2
211
MOA of morphine
mostly mu agonist inhibits ascending pain pathways
212
MOA of hydromorphone
mostly mu agonist and some kappa receptors
213
MOA of ephedrine
direct: alpha and beta agonist indirect: causes release of endogenous catecholamines stored in nerve terminals
214
MOA of phenylephrine
directly activates alpha1 constricts arteries and veins alpha 1>alpha2
214
MOA of epinephrine
beta 2> beta1> alpha1 beta1: inotropy, chronotropy beta2: vasodilation (skeletal muscles) and bronchodilation alpha1: vasoconstriction
215
MOA of dopamine
adrenergic agonist inotropic precursor to norepi alpha1, beta1, beta2, dopaminergic
216
MOA of atropine
inhibits postganglionic muscarinic receptors competes with ACh at the muscarinic receptor sites as an antagonist increases firing of SA node and conduction through the AV node by blocking the action of the vagus nerve
217
MOA of glycopyrrolate
competitively antagonizes ACh at muscarinic receptors
218
MOA of bridion/sugammadex
noncovalently binds to the steroidal muscle relaxant prevents NDNMBs from binding to nicotinic ACh immediate reversal of NDNMB
219
MOA of neostigmine
-anticholinesterase- accumulation of ACh at nicotinic receptors in NMJ -does this by the formation of carbamyl esters -reverses and restores neuromuscular transmission
220
MOA of physostigmine
-anticholinesterase- increases ACh at nicotinic receptors in NMJ -does this by formation of carbamyl esters -more neurotransmitters available for interaction with cholinergic receptors
221
MOA of edrophonium
anticholinesterase- competitive inhibition through electrostatic attachment to the anionic site on the acetylcholinesterase enzyme (presynaptic)
222
MOA of flumazenil
competitive GABA antagonist prevents or reverses effects of benzos
223
MOA of naloxone
competitively antagonizes mu, kappa, delta opioid receptors greatest affinity for MU
224
MOA of hydralazine
activates guanylate cyclase increases cGMP decreases intracellular Ca ateriolar relaxation
225
MOA of labetalol
selective alpha 1 nonselective beta1 and beta 2 blocker
226
MOA of esmolol
selective B1 blocker
227
MOA of ondansetron
5HT3 antagonist blocks serotonin centrally at the CRTZ and peripherally
228
MOA of droperidol
butyrophenone dopamine antagonist at GABA in CRTZ
229
MOA of dexamethasone
-glucocorticoid steroid -derivative of prednisolone -reduces surgery-induced inflammation due to inhibition of prostaglandin synthesis
230
what medication has less myocardial depression than propofol
etomidate
231
what medication can lead to adrenocortical suppression
etomidate
232
what are some CV considerations of etomidate
CV stable less myocardial depression than propofol
233
what are side effects of etomidate
myoclonus pain on injection epileptic foci
234
how is etomidate metabolized
plasma esterases and hepatic enzymes
235
how does etomidate cause adrenocortical suppresssion
inhibits 11 beta hydroxylase
236
what does ketamine do to HR, CO and BP
HR increases BP increases CO increases
237
what is a metabolism consideration with ketamine
redistribution
238
what are 3 side effects of ketamine
hallucinations analgesia increase salivation
239
what are the contraindications of methohexital
porphyria asthma
240
what are signs and symptoms of porphyria
hyponatremia peripheral neuropathy severe abdominal pain psych problems
241
where is propofol metabolized
lungs and liver
242
how is versed eliminated
renal
243
what is the half life of versed
1-4 hrs
244
is versed water soluble
yes
245
what are the short NMBs
succs mivacurium
246
what are the intermediate NMBs
atracurium vec roc cisatracurium
247
what is the long action NMB
pancuronium
248
what is the shortest onset non depolarizing muscle blocker
roc
249
what are considerations for succinylcholine?
metabolized by plasma pseudocholinesterase locks sodium channel can cause MH
250
what is the specific temperature and pH called that causes spontaneous degradation of atracurium
hofman elimination
251
what two NDNMB increase histamine release
mivacurium atracurium
252
what two NMB are eliminated by Hofman elimination or ester hydrolysis
cisatracurium atracurium
253
what are considerations for vecuronium
metabolized more in liver than kidney increased lipid solubility
254
what are considerations for rocuronium
metabolized more in liver than kidney painful injection shortest onset NDNMB
255
what are considerations for pancuronium
increases HR blocks norepi reuptake eliminated in the kidneys
256
what are considerations for fentanyl
rigid chest pulmonary 1st pass effect
257
what is pulmonary 1st pass effect
loss of drug on first circulation through the lungs
258
what are considerations for giving sufentanil
rigid chest pulm 1st pass effect MOST POTENT
259
what are considerations for remifentanil
ultra short acting 6.5 min half life metabolized by hydrolysis esterase
260
what are considerations for merperidine
DO NOT GIVE WITH MAOIs crosses placenta metabolite can cause seizures increase HR used for post op shivering
261
what bp med is selective b1 and a positive inotrope
dobutamine
262
what are considerations for ephedrine admin
does not increase uterine blood flow direct/indirect betal and alpha1
263
what should be done before admin of sugammadex
ptc postetanic count aka twitches
264
what side effects should you look for with neostigmine
cholinergic syndrome decreased HR
265
what class of drug is famotidine
H2 receptor antagonist
266
MOA of famotidine
H2 receptor antagonist that produces selective and reversible inhibition of H2-mediated secretion of hydrogen ions produced by the stomach
267
what is half life and peak of famotidine
half life: 2.5-4 hrs peak: 1-3.5 hrs
268
What NDNMB are supplied in 10mg/ml
Atracurium Rocuronium
269
What NDNMBs are supplied in 2 mg/ml
Mivacurium Cisatracurium And sometimes pancuronium
270
What NDNMBs are supplied in 1mg/ml
Pancuronium Vecuronium
271
Edrophonium MOA
Anticholinesterase Competitive inhibition through electrostatic attachment to the anionic site on the acetylcholinesterase enzyme (presynaptic)
272
Brand name of Sevoflurane
Ultane
273
Brand name for isoflurane
Forane
274
Brand name for desflurane
Suprane
275
Pka of propofol
11
276
Pka of ketamine
3.5-5
277
pyridostigmine dose
0.1-0.3 mg/kg
278
onset and DOA of pyridostigmine
onset 10-20 min doa: 60-120min
279
metabolism and excretion of pyridostigmine
renal 75% liver 25%
280
what anticholinergic do you give with pyridostigmine
glyco
281
what reversals are given with atropine
enlon physostigmine
282
what reversals are given with glyco
neostigmine pyridostigmine
283
which reversal crosses BBB
physostigmine

Anesthesia Meds (7 decks)

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